Evidence map›Paper›PMID 34381549›Full record

ArticleThe Pan African medical journal2021

Clinical profile and management of primary thyroid cancer in patients with nodular goitre at the Douala General Hospital, Cameroon.

Edgar Mandeng Ma Linwa, Esthelle Minka Ngom, Georges Enownchong Enow Orock, Charlotte Eposse Ekoube, Esther Eleonore Ngo Linwa, Ngenge Michael Budzi, Martin Geh Meh, Richard Njock Louis

Open access · greenAbstract read
In one paragraph

Article in The Pan African medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Edgar Mandeng Ma LinwaFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Esthelle Minka NgomFaculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
Georges Enownchong Enow OrockFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Charlotte Eposse EkoubeFaculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
Esther Eleonore Ngo LinwaFaculty of Health Sciences University of Bamenda, Bamenda, Cameroon.
Ngenge Michael BudziFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Martin Geh MehFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Richard Njock LouisFaculty of Medicine and Biomedical Sciences University of Yaoundé I, Yaoundé, Cameroon.
University of Buea · CMUniversity of Douala · CMUniversité de Yaoundé I · CMUniversity of Bamenda · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionthyroid cancer (TC) is considered to have become the fastest growing cancer in terms of incidence worldwide. Despite literature reporting a prevalence of 5-10% in clinically identified thyroid nodules, Cameroon still has limited data on the profile of TCs in patients with Nodular Goitres (NGs). The Objective were to describe the epidemiological, diagnostic and therapeutic profiles of TCs in patients with nodular goitres at the Douala General Hospital (DGH).

methodsthis was a retrospective cross-sectional analysis of patient records with diagnoses of NGs, over 11 years (2006 to 2016) at the DGH.

resultsoverall, 187 patients (mean age= 46.8±13.9 years, men=27 (14.4%)) were included; 43 (23%) cancers were identified. The most common histological type was papillary cancer (50%). Nodule size of >4cm and hypoechogenicity were independently associated with malignancy. Most patients presented with TNM stage II (47.4%) and well-differentiated cancers were considered to be predominantly at low-risk according to MACIS (55%) and AMES (74%) scores. Surgery was offered to 95.3% of patients.

conclusionTCs are frequent in patients with NGs with papillary cancer dominating. A high index of suspicion should be held if a nodule is >4cm and/or is hypoechogenic. Prognostic studies are needed to describe the outcome of TCs in our setting.

Indexed as

AdolescentAdultAgedAged, 80 and overCameroonCarcinoma, PapillaryCross-Sectional StudiesFemaleGoiter, NodularHospitals, GeneralHumansMaleMiddle AgedNeoplasm StagingRetrospective StudiesThyroid NeoplasmsCamerooncancerNodular goitrethyroid

Identifiers

PMID34381549
PMCPMC8325457
OpenAlexW3191902588

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.