Evidence map›Paper›PMID 34381546›Full record

ArticleThe Pan African medical journal2021

Laboratory capacity assessments in 25 African countries at high risk of yellow fever, August-December 2018.

Barbara Wilmot Johnson, Maurice Demanou, Gamou Fall, Jean-Luc Betoulle, Celestina Obiekea, Alison Jane Basile, Cristina Domingo, Christin Goodman, Eric Mossel, Chantal Reusken and 50 more

Abstract read
In one paragraph

Article in The Pan African medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

60 authors.

Barbara Wilmot JohnsonScientific Laboratory Consulting, Laporte, Colorado, United States of America.
Maurice DemanouWorld Health Organization African Region Yellow Fever Laboratory, Ouagadougou, Burkina Faso.
Gamou FallInstitut Pasteur Dakar, Dakar, Senegal.
Jean-Luc BetoulleScientific Laboratory, Atlanta, Georgia, United States of America.
Celestina ObiekeaNational Reference Laboratory, Nigeria Centre for Disease Control, Abuja, Nigeria.
Alison Jane BasileCenters for Disease Control and Prevention, Division of Vector-borne Diseases, Fort Collins, Colorado, United States of America.
Cristina DomingoRobert Koch Institute, Berlin, Germany.
Christin GoodmanCenters for Disease Control and Prevention, Division of Vector-borne Diseases, Fort Collins, Colorado, United States of America.
Eric MosselCenters for Disease Control and Prevention, Division of Vector-borne Diseases, Fort Collins, Colorado, United States of America.
Chantal ReuskenCentre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.
Erin StaplesCenters for Disease Control and Prevention, Division of Vector-borne Diseases, Fort Collins, Colorado, United States of America.
Joana Filipa Machado de MoraisInstituto Nacional de Investigacao em Saude, Luanda, Angola.
Zoraima NetoInstituto Nacional de Investigacao em Saude, Luanda, Angola.
Paula PaixãoInstituto Nacional de Investigacao em Saude, Luanda, Angola.
Yves Eric DenonNational Public Health Laboratory, Cotonou, Benin.
Mariette GlithoNational Public Health Laboratory, Cotonou, Benin.
José MahinouNational Public Health Laboratory, Cotonou, Benin.
Therese KagoneScientific Laboratory Consulting, Laporte, Colorado, United States of America.
Emmanuel NakouneInstitute Pasteur, Bangui, Central African Republic.
Kadidja GamougamHôpital General De Reference Nationale, N'Djamena, Chad.
Elisabeth Pukuta SimbuNational Institute for Biomedical Research, Kinshasha, Democratic Republic of Congo.
Steve AhukaNational Institute for Biomedical Research, Kinshasha, Democratic Republic of Congo.
Jean-Vivien MombouliInstitut National de Santé Publique, Brazzaville, Republic of Congo.
Cynthia Goma-NkouaInstitut National de Santé Publique, Brazzaville, Republic of Congo.
Edgard Valery AdjogouaInstitut Pasteur de Côte d'Ivoire, Abidjan, Côte d'Ivoire.
Adamu TayachewEthiopian Public Health Institute, Virology and Rickettsiology Unit, Addis Ababa, Ethiopia.
Berhane BeyeneWorld Health Organization Laboratory, Ethiopia.
Bakary SannehNational Health Laboratory Services, Royal Victoria Teaching Hospital, Banjul, The Gambia.
Modou Lamin JarjuNational Health Laboratory Services, Royal Victoria Teaching Hospital, Banjul, The Gambia.
Alphonse MendyNational Health Laboratory Services, Royal Victoria Teaching Hospital, Banjul, The Gambia.
Dodzi Kofi AmelorNational Public Health and Reference Laboratory, Public Health Division, Ghana Health Service, Korle-Bu, Accra, Ghana.
Lawrence Ofosu-AppiahNational Public Health and Reference Laboratory, Public Health Division, Ghana Health Service, Korle-Bu, Accra, Ghana.
David OpareNational Public Health and Reference Laboratory, Public Health Division, Ghana Health Service, Korle-Bu, Accra, Ghana.
Lorreta AntwiNational Public Health and Reference Laboratory, Public Health Division, Ghana Health Service, Korle-Bu, Accra, Ghana.
Rexford AdadeNational Public Health and Reference Laboratory, Public Health Division, Ghana Health Service, Korle-Bu, Accra, Ghana.
N'Faly MagassoubaLaboratoire de Reference des Fièvres Hémorragiques, Conakry, Guinée.
Sabado Fernandes GomesLaboratoire National de Sante Publique, Bissau, Guinea-Bissau.
Samson LimbasoCenter for Virus Research, Kenya Medical Research Institute, Nairobi, Kenya.
Joel LutomiahCenter for Virus Research, Kenya Medical Research Institute, Nairobi, Kenya.
Burgess GbeleeNational Public Health Reference Laboratory, National Public Health Institute of Liberia, Charlesville, Liberia.
John DogbaNational Public Health Reference Laboratory, National Public Health Institute of Liberia, Charlesville, Liberia.
Issa CisseInstitut National de Santé Publique Laboratoire de Fièvre Jaune, Bamako, Mali.
Zakou IddeNiamey National Hospital, Niamey, Niger.
Chikwe IhekweazuNational Reference Laboratory, Nigeria Centre for Disease Control, Abuja, Nigeria.
Nwando MbaNational Reference Laboratory, Nigeria Centre for Disease Control, Abuja, Nigeria.
Ousmane FayeInstitut Pasteur Dakar, Dakar, Senegal.
Oumar FayeInstitut Pasteur Dakar, Dakar, Senegal.
Amadou Alpha SallInstitut Pasteur Dakar, Dakar, Senegal.
Zikan KoromaNational Public Health Laboratory, Lakka, Sierra Leone.
Manuela Alphonse JumaNational Public Health Laboratory, Juba, South Sudan.
James Ayei MarorNational Public Health Laboratory, Juba, South Sudan.
Mawahib EldigailPublic Health Laboratory, Khartoum, Sudan.
Adel Hussein EldumaPublic Health Laboratory, Khartoum, Sudan.
Rehab ElagebPublic Health Laboratory, Khartoum, Sudan.
Kossi BadziklouLaboratoire de Sérologie, Institut National d'Hygiène, Lomé, Togo.
Koba Adjaho KomlaLaboratoire de Sérologie, Institut National d'Hygiène, Lomé, Togo.
John KayiwaUganda Virus Research Institute, Entebbe, Uganda.
Julius Julian LutwamaUganda Virus Research Institute, Entebbe, Uganda.
Lee HamptonGavi Secretariat, Geneva, Switzerland.
Mick Norman MuldersDepartment of Immunizations, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland.

Funding

World Health Organization 001
6 · The paper itself

Abstract

introductionaccurate and timely laboratory diagnosis of yellow fever (YF) is critical to the Eliminate Yellow Fever Epidemics (EYE) strategy. Gavi, the Vaccine Alliance recognized the need to support and build capacity in the national and regional laboratories in the Global YF Laboratory Network (GYFLN) as part of this strategy.

methodsto better understand current capacity, gaps and needs of the GYFLN laboratories in Africa, assessments were carried out in national and regional reference laboratories in the 25 African countries at high risk for YF outbreaks that were eligible for new financial support from Gavi.

resultsthe assessments found that the GYFLN in Africa has high capacity but 21% of specimens were not tested due to lack of testing kits or reagents and approximately 50% of presumptive YF cases were not confirmed at the regional reference laboratory due to problems with shipping.

conclusionthe laboratory assessments helped to document the baseline capacities of these laboratories prior to Gavi funding to support strengthening YF laboratories.

Indexed as

Disease OutbreaksAfricaCapacity BuildingEpidemicsHumansLaboratoriesYellow FeverdiagnosticslaboratorytestingYellow fever

Identifiers

PMID34381546
PMCPMC8325472

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.