Evidence map›Paper›PMID 34381538›Full record

ArticleThe Pan African medical journal2021

Association of an empty sella and grave´s disease in a patient with acromegaly: a case report.

Imen Halloul, Asma Ben Abdelkerim, Ghada Saad, Ahlem Slim, Yosra Hasni, Wafa Ben Othman, Maha Kacem, Molka Chaieb, Amel Maaroufi, Koussay Ach

Abstract readCase Reports
In one paragraph

Article in The Pan African medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Imen HalloulEndocrinology and Diabetes Department, Farhat Hached University Hospital, Sousse, Tunisia.
Asma Ben AbdelkerimEndocrinology and Diabetes Department, Farhat Hached University Hospital, Sousse, Tunisia.
Ghada SaadEndocrinology and Diabetes Department, Farhat Hached University Hospital, Sousse, Tunisia.
Ahlem SlimEndocrinology and Diabetes Department, Farhat Hached University Hospital, Sousse, Tunisia.
Yosra HasniEndocrinology and Diabetes Department, Farhat Hached University Hospital, Sousse, Tunisia.
Wafa Ben OthmanEndocrinology and Diabetes Department, Farhat Hached University Hospital, Sousse, Tunisia.
Maha KacemEndocrinology and Diabetes Department, Farhat Hached University Hospital, Sousse, Tunisia.
Molka ChaiebEndocrinology and Diabetes Department, Farhat Hached University Hospital, Sousse, Tunisia.
Amel MaaroufiEndocrinology and Diabetes Department, Farhat Hached University Hospital, Sousse, Tunisia.
Koussay AchEndocrinology and Diabetes Department, Farhat Hached University Hospital, Sousse, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acromegaly is, in most cases, caused by growth hormone secreting pituitary adenomas. Those patients often develop different pathologies of the thyroid gland, however, the occurrence of Grave´s disease is quite a rare situation. We report a case of a 64-year-old female patient who presented with signs of hyperthyroidism and imbalance of her diabetes mellitus. On physical examination, she had facial features of acromegaly. Biochemical testing confirmed the suspicion of acromegaly and Grave´s disease, with an elevated insulin-like growth factor-1 and a suppressed thyroid stimulation hormone (TSH) with positive TSH-receptor antibodies. A pituitary Magnetic Resonance Imaging (MRI) was performed, revealing a macro-adenoma and an empty sella. The patient successfully underwent a transsphenoidal surgery and obtained a remission of her hyperthyroidism under anti-thyroid drugs.

Indexed as

AcromegalyAntithyroid AgentsDiabetes MellitusEmpty Sella SyndromeFemaleGraves DiseaseGrowth Hormone-Secreting Pituitary AdenomaHumansHyperthyroidismInsulin-Like Growth Factor IMagnetic Resonance ImagingMiddle AgedThyrotropinAntithyroid AgentsIGF1 protein, humanInsulin-Like Growth Factor IThyrotropinAcromegalycase reportempty sellagrave´s diseasehyperthyroidism

Identifiers

PMID34381538
PMCPMC8325439

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.