Evidence map›Paper›PMID 34381457›Full record

ArticleFrontiers in immunology2021

ILC1s and ILC3s Exhibit Inflammatory Phenotype in Periodontal Ligament of Periodontitis Patients.

Changyi Li, Jianyue Liu, Jie Pan, Yuhui Wang, Lei Shen, Yan Xu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. ILC3: a case of conflicted identity.Frontiers in immunology · 2023
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Changyi LiDepartment of Orthodontics, Shanghai Stomatological Hospital, Fudan University, Shanghai, China.
Jianyue LiuShanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jie PanDepartment of Orthodontics, Shanghai Stomatological Hospital, Fudan University, Shanghai, China.
Yuhui WangDepartment of Orthodontics, Shanghai Stomatological Hospital, Fudan University, Shanghai, China.
Lei ShenShanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yan XuDepartment of Orthodontics, Shanghai Stomatological Hospital, Fudan University, Shanghai, China.
Shanghai Stomatological Hospital · CNShanghai Jiao Tong University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Innate lymphoid cells (ILCs) are emerging as important players in inflammatory diseases. The oral mucosal barrier harbors all ILC subsets, but how these cells regulate the immune responses in periodontal ligament tissue during periodontitis remains undefined. Here, we show that total ILCs are markedly increased in periodontal ligament of periodontitis patients compared with healthy controls. Among them, ILC1s and ILC3s, particularly NKp44

Indexed as

Immunity, InnateAdultFemaleHumansInterferon-gammaInterleukin-17LymphocytesMaleMiddle AgedNatural Cytotoxicity Triggering Receptor 2Periodontal LigamentPeriodontitisPhenotypeInterferon-gammaInterleukin-17Natural Cytotoxicity Triggering Receptor 2NCR2 protein, humanIFN-γIL-17Ainflammationinnate lymphoid cellsperiodontal ligamentperiodontitis

Identifiers

PMID34381457
PMCPMC8350136
OpenAlexW3187025354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.