Evidence map›Paper›PMID 34381443›Full record

ArticleFrontiers in immunology2021

cDC1 Dependent Accumulation of Memory T Cells Is Required for Chronic Autoimmune Inflammation in Murine Testis.

Yuchao Jing, Min Cao, Bei Zhang, Xuehui Long, Xiaoming Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yuchao JingDepartment of Immunology, Key Laboratory of Immune Microenvironment and Diseases, State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Min CaoDepartment of Immunology, Key Laboratory of Immune Microenvironment and Diseases, State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Bei ZhangDepartment of Immunology, Key Laboratory of Immune Microenvironment and Diseases, State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Xuehui LongDepartment of Immunology, Key Laboratory of Immune Microenvironment and Diseases, State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Xiaoming WangDepartment of Immunology, Key Laboratory of Immune Microenvironment and Diseases, State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As an immune privilege site, there are various types of immune cells in the testis. Previous research has been focused on the testicular macrophages, and much less is known about the T cells in the testis. Here, we found that T cells with memory phenotypes were the most abundant leukocyte in the testis except for macrophages. Our results showed that the proportion of testicular T cells increases gradually from birth to adulthood in mice and that the primary type of T cells changed from γδTCR

Indexed as

Immunologic MemoryAnimalsAutoimmune DiseasesBasic-Leucine Zipper Transcription FactorsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell CommunicationChronic DiseaseDendritic CellsDisease Models, AnimalHumansMaleMiceMice, TransgenicOrchitisRepressor ProteinsBasic-Leucine Zipper Transcription FactorsRepressor ProteinsSNFT protein, mousechronic autoimmune orchitisdendritic cellspermatogenesisT cellstestis

Identifiers

PMID34381443
PMCPMC8350123
OpenAlexW3183608557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.