Evidence map›Paper›PMID 34381364›Full record

ArticleFrontiers in pharmacology2021

Neutral Effects of Combined Treatment With GLP-1R Agonist Exenatide and MR Antagonist Potassium Canrenoate on Cardiac Function in Porcine and Murine Chronic Heart Failure Models.

Evelyne J Demkes, Steven Wenker, Max J M Silvis, Martijn M J van Nieuwburg, M Joyce Visser, Marlijn S Jansen, Maike A D Brans, Evelyn Velema, Joost P G Sluijter, Imo E Hoefer and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Drugs for treating myocardial fibrosis.Frontiers in pharmacology · 2023
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Evelyne J DemkesDepartment of Cardiology, Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
Steven WenkerDepartment of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
Max J M SilvisDepartment of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
Martijn M J van NieuwburgDepartment of Cardiology, Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
M Joyce VisserDepartment of Cardiology, Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
Marlijn S JansenDepartment of Cardiology, Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
Maike A D BransDepartment of Cardiology, Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
Evelyn VelemaDepartment of Cardiology, Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
Joost P G SluijterDepartment of Cardiology, Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
Imo E HoeferCentral Diagnostic Laboratory, University Medical Center Utrecht, Utrecht, Netherlands.
Dominique P V de KleijnDepartment of Vascular Surgery, University Medical Centre Utrecht, Utrecht, Netherlands.
Leo TimmersDepartment of Cardiology, St. Antonius Hospital, Utrecht, Netherlands.
Saskia C A de JagerDepartment of Cardiology, Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
University Medical Center Utrecht · NLUtrecht University · NLSt. Antonius Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cardiac functionchronic heart failureglucagon-like peptide-1 agonistmineralocorticoid receptor antagonistmousemyocardial infarctionporcine

Identifiers

PMID34381364
PMCPMC8352472
OpenAlexW3186858252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.