ArticleFrontiers in human neuroscience2021
Cortical Networks of Creative Ability Trace Gene Expression Profiles of Synaptic Plasticity in the Human Brain.
Article in Frontiers in human neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- The 'hand-brain-emotion' axis: a theoretical model for handicraft art-based intervention in anxiety disorders through neuroplasticity and autonomic regulation.Frontiers in psychology · 2026Review
- Neural, genetic, and cognitive signatures of creativity.Communications biology · 2024Article
- Art therapy and neuroscience: evidence, limits, and myths.Frontiers in psychology · 2024Article
- How the arts heal: a review of the neural mechanisms behind the therapeutic effects of creative arts on mental and physical health.Frontiers in behavioral neuroscience · 2024Article
- Neuroplastin in Neuropsychiatric Diseases.Genes · 2021Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The ability to produce novel ideas is central to societal progress and innovation; however, little is known about the biological basis of creativity. Here, we investigate the organization of brain networks that support creativity by combining functional neuroimaging data with gene expression information. Given the multifaceted nature of creative thinking, we hypothesized that distributed connectivity would not only be related to individual differences in creative ability, but also delineate the cortical distributions of genes involved in synaptic plasticity. We defined neuroimaging phenotypes using a graph theory approach that detects local and distributed network circuits, then characterized the spatial associations between functional connectivity and cortical gene expression distributions. Our findings reveal strong spatial correlations between connectivity maps and sets of genes devoted to synaptic assembly and signaling. This connectomic-transcriptome approach thus identifies gene expression profiles associated with high creative ability, linking cognitive flexibility to neural plasticity in the human brain.
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Registered trials
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