Evidence map›Paper›PMID 34381175›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2022

Growth failure in infants with neonatal abstinence syndrome in the neonatal intensive care unit.

Michael T Favara, Jessica Smith, Daniela Friedman, Margaret Lafferty, David Carola, Susan Adeniyi-Jones, Jay Greenspan, Zubair H Aghai

Abstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Outpatient tapering of buprenorphine in opioid use disorder pregnancies may improve neonatal outcomes.Journal of perinatology : official journal of the California Perinatal Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Michael T FavaraNeonatology, Christiana Care Health System, Newark, DE, USA.
Jessica SmithThomas Jefferson University Hospital, Philadelphia, PA, USA.
Daniela FriedmanThomas Jefferson University Hospital, Philadelphia, PA, USA.
Margaret LaffertyThomas Jefferson University Hospital, Philadelphia, PA, USA.
David CarolaThomas Jefferson University Hospital, Philadelphia, PA, USA.
Susan Adeniyi-JonesThomas Jefferson University Hospital, Philadelphia, PA, USA.
Jay GreenspanThomas Jefferson University Hospital, Philadelphia, PA, USA.
Zubair H AghaiThomas Jefferson University Hospital, Philadelphia, PA, USA. zaghai@nemours.org.ORCID http://orcid.org/0000-0001-5545-9706
Thomas Jefferson University Hospital · USChristiana Care Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess if infants with neonatal abstinence syndrome (NAS) are smaller at birth and have decreased growth parameters between birth and discharge from the neonatal intensive care unit (NICU).

methodsRetrospective data analysis of term/late-preterm neonates with NAS at a single-center NICU between September 2006 and May 2018. Growth parameters (weight, length, HC) were measured at birth and discharge. Z scores and percentiles were calculated using WHO standard growth curves.

resultsA total of 864 infants ≥35 weeks were admitted for NAS. At birth, median percentiles were weight 30%, HC 23%, and length 37%; these decreased significantly (p < 0.001) at discharge to 12%, 6.5%, and 13%, respectively. The percentage of infants <3rd percentile increased significantly (p < 0.001) in all growth parameters from birth to discharge.

conclusionInfants with NAS are smaller at birth and have significant growth retardation in all growth parameters at discharge. An ongoing long-term growth follow-up study will discern the impact of growth restriction in NAS infants.

Indexed as

Neonatal Abstinence SyndromeFemaleFollow-Up StudiesHumansInfantInfant, NewbornIntensive Care Units, NeonatalPatient DischargeRetrospective Studies

Identifiers

PMID34381175
OpenAlexW3191983936

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.