Evidence map›Paper›PMID 34381120›Full record

ArticleScientific reports2021

Molecular and functional characterization of detrusor PDGFRα positive cells in spinal cord injury-induced detrusor overactivity.

Ken Lee, Sang O Park, Pil-Cho Choi, Seung-Bum Ryoo, Haeyeong Lee, Lauren E Peri, Tong Zhou, Robert D Corrigan, Andrew C Yanez, Suk B Moon and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Ken Lee *Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV, 89557, USA.
Sang O Park *Department of Emergency Medicine, Konkuk University School of Medicine, Seoul, South Korea.
Pil-Cho Choi *Department of Emergency Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, Seoul, South Korea.
Seung-Bum Ryoo *Department of Surgery, Seoul National University Hospital, College of Medicine, Seoul National University, Seoul, South Korea.
Haeyeong Lee *Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV, 89557, USA.
Lauren E PeriDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV, 89557, USA.
Tong ZhouDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV, 89557, USA.
Robert D CorriganDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV, 89557, USA.
Andrew C YanezDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV, 89557, USA.
Suk B MoonDepartment of Surgery, School of Medicine, Kangwon National University, Chuncheon, South Korea.
Brian A PerrinoDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV, 89557, USA.
Kenton M SandersDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV, 89557, USA.
Sang Don KohDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV, 89557, USA. skoh@med.unr.edu.
University of Nevada, Reno · USKangbuk Samsung Hospital · KRKangwon National University · KRKonkuk University · KRSeoul National University Hospital · KR

Funding

Molecular and Functional Mechanisms of Purinergic Relaxation in Detrusor MuscleR01DK098388 · NIDDK · UNIVERSITY OF NEVADA RENO · PI KOH, SANG DON · 2013 to 2017
$1.6M
Role of Detrusor Interstitial Cells in Overactive BladderR01DK123237 · NIDDK · UNIVERSITY OF NEVADA RENO · PI KOH, SANG DON · 2020 to 2022
$1.3M
NIDDK NIH HHS R01 DK098388NIDDK NIH HHS R01 DK123237
6 · The paper itself

Abstract

Volume accommodation occurs via a novel mechanism involving interstitial cells in detrusor muscles. The interstitial cells in the bladder are PDGFRα

Indexed as

AnimalsApaminApoptosisGene ExpressionMiceMuscle ContractionReceptor, Platelet-Derived Growth Factor alphaSmall-Conductance Calcium-Activated Potassium ChannelsSpinal Cord InjuriesUrinary BladderUrinary Bladder, OveractiveApaminKcnn3 protein, mouseReceptor, Platelet-Derived Growth Factor alphaSmall-Conductance Calcium-Activated Potassium Channels

Identifiers

PMID34381120
PMCPMC8357952
OpenAlexW3188399927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.