Evidence map›Paper›PMID 34381083›Full record

ArticleScientific reports2021

Taxonomic profiling of skin microbiome and correlation with clinical skin parameters in healthy Koreans.

Ji-Hee Kim, Sang-Mo Son, Hyunjoon Park, Byoung Kook Kim, In Suk Choi, Heebal Kim, Chul Sung Huh

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

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  18. First Animal Source Metagenome Assembly ofPathogens (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ji-Hee KimWCU Biomodulation Major, Department of Agricultural Biotechnology, College of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, South Korea.
Sang-Mo SonWCU Biomodulation Major, Department of Agricultural Biotechnology, College of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, South Korea.
Hyunjoon ParkResearch Institute of Eco-Friendly Livestock Science, Institute of Green-Bio Science and Technology, Pyeongchang-gun, Gangwon-do, 25354, South Korea.
Byoung Kook KimChong Kun Dang Bio Research Institute, Ansan-si, Gyeonggi-do, 15604, South Korea.
In Suk ChoiChong Kun Dang Bio Research Institute, Ansan-si, Gyeonggi-do, 15604, South Korea.
Heebal KimDepartment of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, South Korea.
Chul Sung HuhResearch Institute of Eco-Friendly Livestock Science, Institute of Green-Bio Science and Technology, Pyeongchang-gun, Gangwon-do, 25354, South Korea. chulsunghuh@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interest in skin microbiome differences by ethnicity, age, and gender is increasing. Compared to other ethnic groups, studies on the skin microbiome of Koreans remains insufficient; we investigated facial skin microbiome characteristics according to gender and age among Koreans. Fifty-one healthy participants were recruited, the facial skin characteristics of each donor were investigated, their skin bacterial DNA was isolated and metagenomic analysis was performed. The donors were divided into two groups for age and sex each to analyze their skin microbiomes. Moreover, we investigated the correlation between the skin microbiome and clinical characteristics. The alpha diversity of the skin microbiome was significantly higher in the elderly, and beta diversity was significantly different according to age. The comparative skin microbials showed that the genus Lawsonella was more abundant in the younger age group, and Enhydrobacter was predominant in the older age group. Staphylococcus and Corynebacterium were more abundant in males, while Lactobacillus was more abundant in females. Lawsonella had a negative correlation with skin moisture and brown spots. Staphylococcus and Corynebacterium both had negative correlations with the number of UV spots and positive correlations with transepidermal water loss (TEWL). Furthermore, Staphylococcus aureus had a negative correlation with skin moisture parameters.

Indexed as

Healthy VolunteersAdultAgedAge FactorsAsian PeopleBacteriaDNA Barcoding, TaxonomicFaceFemaleHumansMaleMetagenomicsMiddle AgedSkinWater Loss, InsensibleYoung Adult

Identifiers

PMID34381083
PMCPMC8358022

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.