ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021
Spontaneous Multimodal Neural Transmission Suggests That Adult Spinal Networks Maintain an Intrinsic State of Readiness to Execute Sensorimotor Behaviors.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Ventral intraspinal microstimulation alters neural population-level nociceptive activity in rats including after spinal cord injury.Pain reports · 2026Article
- Human microphysiological model of dorsal root ganglion-spinal cord dorsal horn circuitry recapitulates opioid induced effects.bioRxiv : the preprint server for biology · 2025Article
- Convergent effects of peptides on the initiation of feeding motor programs in the molluskJournal of neurophysiology · 2025Article
- Targeted inactivation of spinal α2 adrenoceptors promotes paradoxical anti-nociception.bioRxiv : the preprint server for biology · 2025Article
- Noise or signal? Spontaneous activity of dorsal horn neurons: patterns and function in health and disease.Pflugers Archiv : European journal of physiology · 2024Review
- Intraspinal microstimulation of the ventral horn has therapeutically relevant cross-modal effects on nociception.Brain communications · 2024Article
- Prediction of isometric forces from combined epidural spinal cord and neuromuscular electrical stimulation in the rat lower limb.Research square · 2023Article
- Precision neuromodulation: Promises and challenges of spinal stimulation for multi-modal rehabilitation.Frontiers in rehabilitation sciences · 2023Article
- Spinal stimulation for motor rehabilitation immediately modulates nociceptive transmission.Journal of neural engineering · 2022Article
- Synchronous firing of dorsal horn neurons at the origin of dorsal root reflexes in naïve and paw-inflamed mice.Frontiers in cellular neuroscience · 2022Article
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Spontaneous action potential discharge (spAP) is both ubiquitous and functionally relevant during neural development. spAP remains a prominent feature of supraspinal networks in maturity, even during unconsciousness. Evidence suggests that spAP persists in mature spinal networks during wakefulness, and one function of spAP in this context could be maintenance of a "ready state" to execute behaviors. The extent to which spAP persists in mature spinal networks during unconsciousness remains unclear, and its function(s), if any, are likewise unresolved. Here, we attempt to reconcile some of the questions and contradictions that emerge from the disintegrated picture of adult spinal spAP currently available. We recorded simultaneously from large populations of spinal interneurons
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.