Evidence map›Paper›PMID 34380717›Full record

ArticleBMJ open2021

Assessing variation among the national essential medicines lists of 21 high-income countries: a cross-sectional study.

Michael Sergio Taglione, Nav Persaud

Abstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Establishing links between drug registers and essential medicines lists.Bulletin of the World Health Organization · 2025
    Article
  4. Review
  5. Essential medicines for mental disorders: comparison of 121 national lists with WHO recommendations.Archives of public health = Archives belges de sante publique · 2023
    Article
  6. Access and use of WHO essential medicines in Italy.Frontiers in public health · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael Sergio TaglioneDepartment of Family and Community Medicine, University of Toronto Faculty of Medicine, Toronto, Ontario, Canada mike.s.taglione@gmail.com.ORCID 0000-0001-8080-7282
Nav PersaudDepartment of Family and Community Medicine, University of Toronto Faculty of Medicine, Toronto, Ontario, Canada.ORCID 0000-0003-3327-5580

Funding

CIHR
6 · The paper itself

Abstract

objectiveEssential medicines lists have been created and used globally in countries that range from low-income to high-income status. The aim of this paper is to compare the essential medicines list of high-income countries with each other, the WHO's Model List of Essential Medicines and the lists of countries of other income statuses.

designHigh-income countries were defined by World Bank classification. High-income essential medicines lists were assessed for medicine inclusion and were compared with the subset of high-income countries, the WHO's Model List and 137 national essential medicines lists. Medicine lists were obtained from the Global Essential Medicines database. Countries were subdivided by income status, and the groups' most common medicines were compared. Select medicines and medicine classes were assessed for inclusion among high-income country lists.

resultsThe 21 high-income countries identified were most like each other when compared with other lists. They were more like upper middle-income countries and least like low-income countries. There was significant variability in the number of medicines on each list. Less than half (48%) of high-income countries included a newer diabetes medicines in their list. Most countries (71%) included naloxone while every country including at least one opioid medicine. More than half of the lists (52%) included a medicine that has been globally withdrawn or banned.

conclusionEssential medicines lists of high-income countries are similar to each other, but significant variations in essential medicine list composition and specifically the number of medications included were noted. Effective medicines were left off several countries' lists, and globally recalled medicines were included on over half the lists. Comparing the essential medicines lists of countries within the same income status category can provide a useful subset of lists for policymakers and essential medicine list creators to use when creating or maintaining their lists.

Indexed as

Drugs, EssentialCross-Sectional StudiesDeveloped CountriesDeveloping CountriesHumansIncomeWorld Health OrganizationDrugs, Essentialhealth policyinternational health servicespublic health

Identifiers

PMID34380717
PMCPMC8359480

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.