Evidence map›Paper›PMID 34380576›Full record

ArticleBMC rheumatology2021

Coronary artery aneurysms in children is not always Kawasaki disease: a case report on Takayasu arteritis.

Michelle Lee, Esra Meidan, MaryBeth Son, Audrey Dionne, Jane W Newburger, Kevin G Friedman

Open access · goldAbstract read
In one paragraph

Article in BMC rheumatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Overlap of Takayasu Arteritis and Kawasaki Disease in Infants.Chronic diseases and translational medicine · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Michelle LeeDepartment of Pediatrics, Harvard Medical School, Boston, MA, USA. michelle_lee2@hms.harvard.edu.
Esra MeidanDepartment of Pediatrics, Harvard Medical School, Boston, MA, USA.
MaryBeth SonDepartment of Pediatrics, Harvard Medical School, Boston, MA, USA.
Audrey DionneDepartment of Cardiology, Boston Children's Hospital, 300 Longwood Avenue- Farley 2, Boston, MA, 02115, USA.
Jane W NewburgerDepartment of Cardiology, Boston Children's Hospital, 300 Longwood Avenue- Farley 2, Boston, MA, 02115, USA.
Kevin G FriedmanDepartment of Cardiology, Boston Children's Hospital, 300 Longwood Avenue- Farley 2, Boston, MA, 02115, USA.
Boston Children's Hospital · USHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronary artery (CA) aneurysms in children are a rare but potentially life-threatening finding and are highly associated with Kawasaki disease (KD). CASE PRESENTATION: We describe a four-year-old female with a vasculitis and CA aneurysms. She had a prolonged course with recurrent fever and systemic inflammation several times upon discontinuation of steroid treatment. Due in part to the CA aneurysms, she initially was diagnosed with KD but due to the unusual clinical course, further evaluation was performed. Abdominal and chest MRI/A revealed diffuse aortitis suggestive of a large vessel vasculitis, specifically Takayasu arteritis. With treatment targeted for Takayasu arteritis, there was resolution of fever and inflammation and the CA aneurysms improved.

conclusionsThis case demonstrates the utility in broadening the differential diagnosis in cases of presumed KD with CA involvement in which the clinical course is atypical for KD.

Indexed as

Case reportCoronary artery aneurysmKawasaki diseaseTakayasu’s arteritis

Identifiers

PMID34380576
PMCPMC8357446
OpenAlexW3187719606

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.