Evidence map›Paper›PMID 34380492›Full record

ArticleBMC health services research2021

Barriers to medication adherence in a rural-urban dual economy: a multi-stakeholder qualitative study.

Jacqueline Xu, Mengxi Zhao, Athina Vrosgou, Natalie Chin Wen Yu, Chelsea Liu, Han Zhang, Chunxi Ding, Noelle Wyman Roth, Yuesong Pan, Liping Liu and 3 more

Abstract read
In one paragraph

Article in BMC health services research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jacqueline XuTrinity College of Arts and Sciences, Duke University, Durham, NC, USA. xu.jacqueline@gmail.com.
Mengxi ZhaoDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Athina VrosgouTrinity College of Arts and Sciences, Duke University, Durham, NC, USA.
Natalie Chin Wen YuTrinity College of Arts and Sciences, Duke University, Durham, NC, USA.
Chelsea LiuTrinity College of Arts and Sciences, Duke University, Durham, NC, USA.
Han ZhangTrinity College of Arts and Sciences, Duke University, Durham, NC, USA.
Chunxi DingTrinity College of Arts and Sciences, Duke University, Durham, NC, USA.
Noelle Wyman RothSocial Science Research Institute, Duke University, Durham, NC, USA.
Yuesong PanDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Liping LiuDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yilong WangDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yongjun WangDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Janet Prvu BettgerDepartment of Orthopaedics, Duke University School of Medicine, Durham, NC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOne of the most cost-effective treatments for secondary prevention of stroke and other non-communicable diseases is a long-term medication regimen. However, the complexities of medication adherence extend far beyond individual behavior change, particularly in low- and middle-income countries. The purpose of this study was to examine stakeholder perspectives on barriers to medication adherence for stroke patients in Beijing, China, identifying opportunities to improve care and policy in resource-constrained settings.

methodsWe conducted a qualitative, phenomenological analysis of data obtained from 36 individuals. Participants were patients; caregivers; healthcare providers; and representatives from industry and government, purposively selected to synthesize multiple perspectives on medication management and adherence for stroke secondary prevention in Beijing, China. Data was analyzed by thematic analysis across iterative coding cycles.

resultsFour major themes characterized barriers on medication adherence, across stakeholders and geographies: limitations driven by individual patient knowledge / attitudes; lack of patient-provider interaction time; lack of coordination across the stratified health system; and lack of affordability driven by high overall costs and limited insurance policies.

conclusionsThese barriers to medication management and adherence suggest opportunities for policy reform and local practice changes, particularly for multi-tiered health systems. Findings from this study in Beijing, China could be explored for applicability in other low- and middle-income countries with urban centers serving large geographic regions.

Indexed as

CaregiversMedication AdherenceHumansQualitative ResearchRural PopulationSecondary PreventionDeveloping CountriesMedication AdherenceNoncommunicable DiseasesQualitative ResearchStroke

Identifiers

PMID34380492
PMCPMC8359298

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.