Evidence map›Paper›PMID 34380481›Full record

ArticleBMC veterinary research2021

Impact of region-of-interest size and location on quantitative contrast-enhanced ultrasound of canine splenic perfusion.

Simona Morabito, Simona Di Pietro, Luca Cicero, Annastella Falcone, Luigi Liotta, Rosalia Crupi, Giovanni Cassata, Francesco Macrì

Open access · goldAbstract readObservational Study, Veterinary
In one paragraph

Article in BMC veterinary research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Simona Morabito *Department of Veterinary Sciences, University of Messina, Polo Universitario Annunziata, 98168, Messina, Italy.
Simona Di Pietro *Department of Veterinary Sciences, University of Messina, Polo Universitario Annunziata, 98168, Messina, Italy.
Luca CiceroIstituto Zooprofilattico Sperimentale della Sicilia "A. Mirri", Via Gino Marinuzzi 3, 90100, Palermo, Italy. cicero.luca@libero.it.
Annastella FalconeDepartment of Veterinary Sciences, University of Messina, Polo Universitario Annunziata, 98168, Messina, Italy.
Luigi LiottaDepartment of Veterinary Sciences, University of Messina, Polo Universitario Annunziata, 98168, Messina, Italy.
Rosalia CrupiDepartment of Veterinary Sciences, University of Messina, Polo Universitario Annunziata, 98168, Messina, Italy.
Giovanni CassataIstituto Zooprofilattico Sperimentale della Sicilia "A. Mirri", Via Gino Marinuzzi 3, 90100, Palermo, Italy.
Francesco MacrìDepartment of Veterinary Sciences, University of Messina, Polo Universitario Annunziata, 98168, Messina, Italy.
University of Messina · ITIstituto Zooprofilattico Sperimentale Della Sicilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring contrast enhanced ultrasound (CEUS), the features of the regions of interest (ROI) can affect the value of the perfusion-related parameters obtained from a time intensity curve (TIC). In veterinary medicine, conflicting have been reported on the influence of ROI size and location on renal CEUS. There are some disagreeing evidences regarding the optimal method for selecting ROI in quantitative analysis of renal perfusion using CEUS. The aim of this study was to evaluate the effect of the size and location of ROIs in the spleen of conscious dogs on perfusion variables determined using sulphur hexafluoride contrast-enhanced ultrasounds.

resultsA prospective observational study on 15 client-owned mixed-breed adult dogs was performed using a system equipped with contrast-tuned imaging technology. Qualitative and quantitative assessments of the spleen enhancement pattern were carried out. Three square ROIs (0.05 cm

conclusionsThe recommendation for a quantitative CEUS examination of a dog's spleen is to analyze splenic perfusion by drawing a sufficiently large ROI proximal to the ultrasound beam on the splenic parenchyma. This may be of clinical relevance in the diagnosis of splenic diseases.

Indexed as

DogsAnimalsContrast MediaFemaleMaleProspective StudiesSpleenUltrasonographyContrast MediaCoefficient of variationDogPerfusion-related parametersQontrastSonovueSpleen

Identifiers

PMID34380481
PMCPMC8356454
OpenAlexW3191756235

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.