Evidence map›Paper›PMID 34380433›Full record

ArticleBMC neurology2021

Impact of stroke history on the presence of cerebral microbleeds in hemodialysis patients.

Toshihide Naganuma, Daijiro Kabata, Yoshiaki Takemoto, Junji Uchida, Ayumi Shintani

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Toshihide NaganumaDepartment of Urology, Osaka City University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, Osaka, 545-8585, Japan. spxd48k9@aria.ocn.ne.jp.
Daijiro KabataDepartment of Medical Statistics, Osaka City University, Osaka, Osaka, Japan.
Yoshiaki TakemotoDepartment of Urology, Osaka City University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, Osaka, 545-8585, Japan.
Junji UchidaDepartment of Urology, Osaka City University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, Osaka, 545-8585, Japan.
Ayumi ShintaniDepartment of Medical Statistics, Osaka City University, Osaka, Osaka, Japan.
Osaka City University Hospital · JPOsaka City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCerebral microbleeds (CMBs) are detected on gradient-echo T2*-weighted magnetic resonance imaging (MRI). Clinically, CMBs are often detected after stroke, including in cases of intracerebral hemorrhage and ischemic cerebrovascular disease. Hemodialysis (HD) patients are widely known to have a high incidence of stroke, and HD patients without stroke history have been reported to have a high prevalence of CMBs. In this study, we investigated whether history of stroke affects the prevalence of CMBs in HD patients.

methodsA cross-sectional study was performed in 241 HD patients who underwent brain T2*-weighted MRI. We compared the prevalence of CMBs between the patients with and without a history of stroke. Moreover, the relationship between history of stroke and presence of CMBs was examined by multivariate logistic regression analysis.

resultsAmong these patients, 22 (9.1%) had a history of stroke. CMBs were detected in 70 patients (29.0%). The prevalence of CMBs was significantly higher in patients with a history of stroke compared to those without this history (54.5 vs. 26.5%, p = 0.012). In the multivariable analysis adjusted for background characteristics, history of stroke was a significant and independent factor related to CMBs (OR: 3.24, 95%CI: 1.18-8.89, p = 0.02). DISCUSSION/

conclusionsAs has been reported for non-dialysis patients, our results showed a high prevalence of CMBs in HD patients with a history of stroke, and indicated that a history of stroke is significantly and independently associated with CMBs in HD patients.

Indexed as

StrokeCerebral HemorrhageCross-Sectional StudiesHumansMagnetic Resonance ImagingRenal DialysisCerebral microbleedsDialysisMedical historyStroke

Identifiers

PMID34380433
PMCPMC8356420
OpenAlexW3188794937

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.