Evidence map›Paper›PMID 34380115›Full record

ArticleBiofabrication2021

3D printing of sacrificial thioester elastomers using digital light processing for templating 3D organoid structures in soft biomatrices.

Benjamin J Carberry, John E Hergert, F Max Yavitt, Juan J Hernandez, Kelly F Speckl, Christopher N Bowman, Robert R McLeod, Kristi S Anseth

Abstract read
In one paragraph

Article in Biofabrication, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Adaptive PEG Bis-dendron Hydrogels with Tunable Mechanics and Bioactivity.Chemistry of materials : a publication of the American Chemical Society · 2026
    Article
  3. Review
  4. Article
  5. A review of 3D bioprinting for organoids.Medical review (2021) · 2025
    Review
  6. Review
  7. Lithography-based 3D printing of hydrogels.Nature reviews bioengineering · 2025
    Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Light-based vat-polymerization bioprinting.Nature reviews. Methods primers · 2023
    Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Benjamin J CarberryDepartment of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO 80303, United States of America.
John E HergertMaterials Science and Engineering, University of Colorado, Boulder, CO 80309, United States of America.
F Max YavittDepartment of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO 80303, United States of America.
Juan J HernandezDepartment of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO 80303, United States of America.ORCID 0000-0003-0040-0904
Kelly F SpecklDepartment of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO 80303, United States of America.
Christopher N BowmanDepartment of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO 80303, United States of America.
Robert R McLeodMaterials Science and Engineering, University of Colorado, Boulder, CO 80309, United States of America.
Kristi S AnsethDepartment of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO 80303, United States of America.ORCID 0000-0002-5725-5691

Funding

Osteogenic Hydrogel Niches to Promote hMSC Migration and DifferentiationR01DE016523 · NIDCR · UNIVERSITY OF COLORADO AT BOULDER · PI ANSETH, KRISTI S. · 2005 to 2023
$6.2M
Ex Vivo Expansion of Human Limbal Stem Cells for TransplantationR01EY021797 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Sophie Deng · 2012 to 2026
$5.1M
Synthetic hydrogels to study formation and maintenance of intestinal cryptsR01DK120921 · NIDDK · UNIVERSITY OF COLORADO · PI KRISTI S. ANSETH, PETER J DEMPSEY · 2019 to 2026
$3.8M
Understanding the intestinal regenerative response using patterned organoids in photo-tunable PEG hydrogelsF31DK126427 · NIDDK · UNIVERSITY OF COLORADO · PI YAVITT, MAX · 2021 to 2023
$114k
NEI NIH HHS R01 EY021797NIDCR NIH HHS R01 DE016523NIDDK NIH HHS F31 DK126427NIDDK NIH HHS R01 DK120921
6 · The paper itself

Abstract

Biofabrication allows for the templating of structural features in materials on cellularly-relevant size scales, enabling the generation of tissue-like structures with controlled form and function. This is particularly relevant for growing organoids, where the application of biochemical and biomechanical stimuli can be used to guide the assembly and differentiation of stem cells and form architectures similar to the parent tissue or organ. Recently, ablative laser-scanning techniques was used to create 3D overhang features in collagen hydrogels at size scales of 10-100

Indexed as

ElastomersOrganoidsHydrogelsPolyethylene GlycolsPrinting, Three-DimensionalElastomersHydrogelsPolyethylene Glycols3D printingbiofabricationcovalent adaptable networksintestinal organoidsstimuli-induced degradationthioester exchange

Identifiers

PMID34380115
PMCPMC8860055

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.