Evidence map›Paper›PMID 34380096›Full record

ArticleJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2021

Evaluation of a high volume antigen test for detection of SARS-CoV-2.

Paul N Levett, Branco Cheung, Jesse Kustra, Tamara Pidduck, Annie Mak, Frankie Tsang, Martin Petric, Mel Krajden

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Paul N LevettBritish Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address: paul.levett@bccdc.ca.
Branco CheungBritish Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
Jesse KustraBritish Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
Tamara PidduckBritish Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
Annie MakBritish Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
Frankie TsangBritish Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
Martin PetricDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Mel KrajdenBritish Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
BC Centre for Disease Control · CAUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing transmission of SARS-CoV-2 infection in successive waves may strain the capacity of laboratories performing molecular diagnostic testing. Alternative testing approaches may offer additional diagnostic capacity. A high throughput chemiluminescent antigen assay (Ortho VITROS SARS-CoV-2 antigen test) was evaluated using both an inactivated virus preparation and prospective clinical samples (nasopharyngeal swabs in virus transport medium). The limit of detection of the assay was approximately 0.5 TCID

Indexed as

COVID-19SARS-CoV-2HumansNasopharynxProspective StudiesSensitivity and Specificityantigen detectionCOVID-19SARS-CoV-2

Identifiers

PMID34380096
PMCPMC8327635
OpenAlexW3192804890

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.