Evidence map›Paper›PMID 34380058›Full record

ArticleImmunity2021

Smooth-talking T cells leave asthma breathless.

Artem Romanov, Sonia Sharma

Open access · bronzeAbstract readComment
In one paragraph

Article in Immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Artem RomanovLa Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Sonia SharmaLa Jolla Institute for Immunology, La Jolla, CA 92037, USA. Electronic address: soniasharma@lji.org.
La Jolla Institute for Immunology · US

Funding

Bioactive Metabolites Modulate Immune-Related Adverse Events in Cancer ImmunotherapyR01CA256133 · NCI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI DENNIS, EDWARD A, SHARMA, SONIA · 2021 to 2025
$3.5M
NCI NIH HHS R01 CA256133
6 · The paper itself

Abstract

The plasma membrane channel PANX1 mediates release of bio-active adenine nucleotides; however, its function in immune cells is unknown. In this issue of Immunity, Medina et al. show that PANX1 mediates adenosine-dependent communication between regulatory and effector CD4

Indexed as

AsthmaConnexinsHumansInflammationNerve Tissue ProteinsRespiratory SystemConnexinsNerve Tissue ProteinsPANX1 protein, human

Identifiers

PMID34380058
PMCPMC10151120
OpenAlexW3190799754

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.