Evidence map›Paper›PMID 34379857›Full record

ArticleMolecular microbiology2021

Bacteriophage λ RexA and RexB functions assist the transition from lysogeny to lytic growth.

Lynn C Thomason, Carl J Schiltz, Carolyn Court, Christopher J Hosford, Myfanwy C Adams, Joshua S Chappie, Donald L Court

Open access · greenAbstract read
In one paragraph

Article in Molecular microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Prophage: agent provocateur?Archives of microbiology · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Hybrid Vigor: Importance of Hybrid λ Phages in Early Insights in Molecular Biology.Microbiology and molecular biology reviews : MMBR · 2022
    Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lynn C ThomasonBasic Science Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.ORCID 0000-0002-1699-3807
Carl J SchiltzDepartment of Molecular Medicine, Cornell University, Ithaca, New York, USA.
Carolyn CourtRNA Biology Laboratory, National Cancer Institute/Frederick Cancer Research and Development Center, Frederick, Maryland, USA.
Christopher J HosfordDepartment of Molecular Medicine, Cornell University, Ithaca, New York, USA.
Myfanwy C AdamsDepartment of Molecular Medicine, Cornell University, Ithaca, New York, USA.
Joshua S ChappieDepartment of Molecular Medicine, Cornell University, Ithaca, New York, USA.ORCID 0000-0002-5733-7275
Donald L CourtRNA Biology Laboratory, National Cancer Institute/Frederick Cancer Research and Development Center, Frederick, Maryland, USA.
Cornell University · USFrederick National Laboratory for Cancer Research · US

Funding

Intramural NIH HHS Z99 CA999999NCI NIH HHS HHSN26120080001E
6 · The paper itself

Abstract

The CI and Cro repressors of bacteriophage λ create a bistable switch between lysogenic and lytic growth. In λ lysogens, CI repressor expressed from the P

Indexed as

DNA ReplicationLysogenyBacteriophage lambdaDNA, ViralGene Expression Regulation, ViralGenes, ViralPromoter Regions, GeneticRepressor ProteinsViral Nonstructural ProteinsViral ProteinsViral Regulatory and Accessory ProteinsDNA, Viralphage repressor proteinsRepressor ProteinsRexA protein, Bacteriophage lambdarexB protein, Bacteriophage lambdaViral Nonstructural ProteinsViral ProteinsViral Regulatory and Accessory Proteinsbacteriophage λgenetic switchlysogenylytic growthphage developmentprophage

Identifiers

PMID34379857
PMCPMC8541928
OpenAlexW3191670772

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.