Evidence map›Paper›PMID 34379820›Full record

ArticleEnvironmental toxicology and chemistry2021

Biotransformation Potential of Cationic Surfactants in Fish Assessed with Rainbow Trout Liver S9 Fractions.

Steven T J Droge, James M Armitage, Jon A Arnot, Patrick N Fitzsimmons, John W Nichols

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental toxicology and chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Environmental science & technology · 2022
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Steven T J DrogeInstitute for Biodiversity and Ecosystem Dynamics, University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-1193-1850
James M ArmitageAES Armitage Environmental Sciences, Ottawa, Ontario, Canada.
Jon A ArnotARC Arnot Research and Consulting, Toronto, Ontario, Canada.ORCID 0000-0002-4295-4270
Patrick N FitzsimmonsGreat Lakes Toxicology and Ecology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Duluth, Minnesota.
John W NicholsGreat Lakes Toxicology and Ecology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Duluth, Minnesota.
Environmental Protection Agency · USARC Resources (Canada) · CAASL Environmental Sciences (Canada) · CAUniversity of Amsterdam · NL

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

Biotransformation may substantially reduce the extent to which organic environmental contaminants accumulate in fish. Presently, however, relatively little is known regarding the biotransformation of ionized chemicals, including cationic surfactants, in aquatic organisms. To address this deficiency, a rainbow trout liver S9 substrate depletion assay (RT-S9) was used to measure in vitro intrinsic clearance rates (CL

Indexed as

Oncorhynchus mykissAnimalsBiotransformationLiverMetabolic Clearance RateSurface-Active AgentsSurface-Active AgentsBioaccumulationBiotransformationContaminants of emerging concernIn vitro toxicologyLiver S9Personal care productsRainbow trout

Identifiers

PMID34379820
PMCPMC9187044
OpenAlexW3190090485

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.