ArticlePloS one2021
COVID-19 severity: Studying the clinical and demographic risk factors for adverse outcomes.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global prevalence of coronavirus disease 2019 reinfection: a systematic review and meta-analysis.BMC public health · 2023Pooled it
- Article
- "Locked in a Jail Cell in Your Own Home": Child Maltreatment Investigators' Perspectives of COVID-19's Effects on Maltreated Children.Child maltreatment · 2024Article
- Cycle threshold (Ct)values of SARS-CoV2 vary with the type of symptoms and comorbidities of the patients.Molecular biology reports · 2024Article
- Prognostic value of interleukin-6 serum levels in hospitalized COVID-19 patients: A case-control study in Iran.Health science reports · 2024Article
- Effect of nasal carriage ofMicrobiology spectrum · 2024Article
- Predictors of developing severe COVID-19 among hospitalized patients: a retrospective study.Frontiers in medicine · 2024Article
- COVID-Net Biochem: an explainability-driven framework to building machine learning models for predicting survival and kidney injury of COVID-19 patients from clinical and biochemistry data.Scientific reports · 2023Article
- An epidemiological evaluation of COVID-19 in La paz, Bolivia.Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2023Article
- Prevention and treatment of COVID-19 infection by earthing.Biomedical journal · 2023Observational
- Review
- Population-level median cycle threshold (Ct) values for asymptomatic COVID-19 cases can predict the trajectory of future cases.PloS one · 2023Article
- Risk factors for COVID-19 mortality among telehealth patients in Bangladesh: A prospective cohort study.PLOS global public health · 2023Article
- Treatment-Seeking Behavior of Patients With COVID-19 and Its Related Factors in Central Sulawesi, Indonesia.Asia-Pacific journal of public health · 2022Article
- Generation of Cytotoxic T Cells and Dysfunctional CD8 T Cells in Severe COVID-19 Patients.Cells · 2022Article
- Factors associated with cycle threshold values (Ct-values) of SARS-CoV2-rRT-PCR.Molecular biology reports · 2022Article
- Projecting the Pandemic Trajectory through Modeling the Transmission Dynamics of COVID-19.International journal of environmental research and public health · 2022Article
- Article
- Factors Associated for COVID19 Severity Among Patients Treated at Selgalu Treatment Center Assosa in Ethiopia: A Case-Control Study.International journal of general medicine · 2022Article
- Profile of Secondary Bacterial and Fungal Infections in Hospitalized COVID-19 Patients in a Tertiary Care Centre.Infection and drug resistance · 2022Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe primary goal of the presented cross-sectional observational study was to determine the clinical and demographic risk factors for adverse coronavirus disease 2019 (COVID-19) outcomes in the Pakistani population.
methodsWe examined the individuals (n = 6331) that consulted two private diagnostic centers in Lahore, Pakistan, for COVID-19 testing between May 1, 2020, and November 30, 2020. The attending nurse collected clinical and demographic information. A confirmed case of COVID-19 was defined as having a positive result through real-time reverse transcriptase polymerase chain reaction (RT-PCR) assay of nasopharyngeal swab specimens.
resultsRT-PCR testing was positive in 1094 cases. Out of which, 5.2% had severe, and 20.8% had mild symptoms. We observed a strong association of COVID-19 severity with the number and type of comorbidities. The severity of the disease intensified as the number of comorbidities increased. The most vulnerable groups for the poor outcome are patients with diabetes and hypertension. Increasing age was also associated with PCR positivity and the severity of the disease.
conclusionsMost cases of COVID-19 included in this study developed mild symptoms or were asymptomatic. Risk factors for adverse outcomes included older age and the simultaneous presence of comorbidities.
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