Evidence map›Paper›PMID 34379510›Full record

ArticleJournal of virology2021

Zika Virus Infection of Pregnant

Ellie K Bohm, Jennifer T Vangorder-Braid, Anna S Jaeger, Ryan V Moriarty, John J Baczenas, Natalie C Bennett, Shelby L O'Connor, Michael K Fritsch, Nicole A Fuhler, Kevin K Noguchi and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  4. Review
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  8. Article
  9. Article
  10. Article
  11. Pathogenesis of Zika Virus Infection.Annual review of pathology · 2023
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Ellie K BohmDepartment of Veterinary and Biomedical Sciences, University of Minnesota,grid.17635.36 Twin Cities, St. Paul, Minnesota, USA.
Jennifer T Vangorder-BraidDepartment of Veterinary and Biomedical Sciences, University of Minnesota,grid.17635.36 Twin Cities, St. Paul, Minnesota, USA.
Anna S JaegerDepartment of Veterinary and Biomedical Sciences, University of Minnesota,grid.17635.36 Twin Cities, St. Paul, Minnesota, USA.
Ryan V MoriartyDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
John J BaczenasWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Natalie C BennettDepartment of Veterinary and Biomedical Sciences, University of Minnesota,grid.17635.36 Twin Cities, St. Paul, Minnesota, USA.
Shelby L O'ConnorDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Michael K FritschDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Nicole A FuhlerDepartment of Psychiatry, Washington University in St. Louisgrid.4367.6, St. Louis, Missouri, USA.
Kevin K NoguchiDepartment of Psychiatry, Washington University in St. Louisgrid.4367.6, St. Louis, Missouri, USA.
Matthew T AliotaDepartment of Veterinary and Biomedical Sciences, University of Minnesota,grid.17635.36 Twin Cities, St. Paul, Minnesota, USA.ORCID 0000-0002-6902-9149
University of Minnesota · USUniversity of Wisconsin–Madison · USWashington University in St. Louis · US

Funding

WUIDDRC Supplement-Supporting the health and well-being of children with intellectual and developmental disability during COVID-19 pandemicP50HD103525 · NICHD · WASHINGTON UNIVERSITY · PI JEFFREY D MILBRANDT · 2020 to 2026
$15.5M
Minnesota Training Program in VirologyT32AI083196 · NIAID · UNIVERSITY OF MINNESOTA · PI Louis M Mansky · 2010 to 2026
$3.2M
Previous exposure to dengue as a risk factor for Zika during pregnancyR01AI132563 · NIAID · UNIVERSITY OF MINNESOTA · PI ALIOTA, MATTHEW T · 2018 to 2022
$2.8M
HHS | National Institutes of Health (NIH) R01AI132563HHS | National Institutes of Health (NIH) T32AI083196NIAID NIH HHS R01 AI132563NIAID NIH HHS T32 AI083196NICHD NIH HHS P50 HD103525
6 · The paper itself

Abstract

Zika virus (ZIKV) is a flavivirus that causes a constellation of adverse fetal outcomes collectively termed congenital Zika syndrome (CZS). However, not all pregnancies exposed to ZIKV result in an infant with apparent defects. During the 2015 to 2016 American outbreak of ZIKV, CZS rates varied by geographic location. The underlying mechanisms responsible for this heterogeneity in outcomes have not been well defined. Therefore, we sought to characterize and compare the pathogenic potential of multiple Asian-/American-lineage ZIKV strains in an established

Indexed as

AnimalsDisease Models, AnimalFemaleFetusMaleMiceMice, Inbred C57BLMice, KnockoutPlacentaPregnancyPregnancy Complications, InfectiousReceptor, Interferon alpha-betaZika Virus InfectionIfnar1 protein, mouseReceptor, Interferon alpha-betacongenital Zika syndromeFlaviviridaeflaviviruspregnancyZika virus

Identifiers

PMID34379510
PMCPMC8513483
OpenAlexW3187856749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.