Evidence map›Paper›PMID 34379277›Full record

Trial reportJournal of general internal medicine2022

Blood Pressure Visit Intensification in Treatment (BP-Visit) Findings: a Pragmatic Stepped Wedge Cluster Randomized Trial.

Kevin Fiscella, Hua He, Mechelle Sanders, Andrea Cassells, Jennifer K Carroll, Stephen K Williams, Jerry Cornell, Tameir Holder, Chamanara Khalida, Jonathan N Tobin

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in Journal of general internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02164331 (A Multimodal Quality Improvement Intervention Using the JNC Guidelines to Promote Control of Patients' BP in Federally Qualified Health Centers), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02164331 nacompletednot on this map

A Multimodal Quality Improvement Intervention Using the JNC Guidelines to Promote Control of Patients' BP in Federally Qualified Health Centers

TypeinterventionalSponsorUniversity of RochesterRan2013 to 2017Enrolled76ConditionsBlood Pressure, HypertensionArmsJNC guideline training
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Kevin FiscellaUniversity of Rochester, Rochester, NY, USA. Kevin_Fiscella@URMC.rochester.edu.ORCID 0000-0003-3613-8012
Hua HeTulane University, New Orleans, LA, USA.
Mechelle SandersUniversity of Rochester, Rochester, NY, USA.
Andrea CassellsClinical Directors Network (CDN), New York, NY, USA.
Jennifer K CarrollUniversity of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
Stephen K WilliamsNYU Langone Health, New York, NY, USA.
Jerry CornellFamily Medicine Research, 1381 South Ave, Rochester, NY, 14620, USA.
Tameir HolderTulane University, New Orleans, LA, USA.
Chamanara KhalidaTulane University, New Orleans, LA, USA.
Jonathan N TobinTulane University, New Orleans, LA, USA.
Tulane University · USUniversity of Rochester · USClinical Directors Network · USNYU Langone Health · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Rochester Medical Center · US

Funding

The University of Rochester's Clinical and Translational Science InstituteUL1TR002001 · NCATS · UNIVERSITY OF ROCHESTER · PI WILSON, KAREN M., ZAND, MARTIN S · 2016 to 2024
$34.6M
Blood Pressure-Visit Intensification for Successful Improvement of TreatmentR18HL117801 · NHLBI · UNIVERSITY OF ROCHESTER · PI FISCELLA, KEVIN ANTHONY, TOBIN, JONATHAN N · 2013 to 2017
$3.3M
N2: Building a Network of Safety Net PBRNsP30HS021667 · AHRQ · CLINICAL DIRECTORS NETWORK, INC. · PI TOBIN, JONATHAN N · 2012 to 2016
$595k
AHRQ HHS 1 P30-HS-021667AHRQ HHS P30 HS021667NCATS NIH HHS UL1 TR002001NHLBI NIH HHS 1R18HL117801NHLBI NIH HHS R18 HL117801
6 · The paper itself

Abstract

backgroundShortening time between office visits for patients with uncontrolled hypertension represents a potential strategy for improving blood pressure (BP).

objectiveWe evaluated the impact of multimodal strategies on time between visits and on improvement in systolic BP (SBP) among patients with uncontrolled hypertension.

designWe used a stepped-wedge cluster randomized controlled trial with three wedges involving 12 federally qualified health centers with three study periods: pre-intervention, intervention, and post-intervention.

participantsAdult patients with diagnosed hypertension and two BPs ≥ 140/90 pre-randomization and at least one visit during post-randomization control period (N = 4277).

interventionThe core intervention included three, clinician hypertension group-based trainings, monthly clinician feedback reports, and monthly meetings with practice champions to facilitate implementation. MAIN MEASURES: The main measures were change in time between visits when BP was not controlled and change in SBP. A secondary planned outcome was changed in BP control among all hypertension patients in the practices. KEY

resultsMedian follow-up times were 34, 32, and 32 days and the mean SBPs were 142.0, 139.5, and 139.8 mmHg, respectively. In adjusted analyses, the intervention did not improve time to the next visit compared with control periods, HR = 1.01 (95% CI: 0.98, 1.04). SBP was reduced by 1.13 mmHg (95% CI: -2.10, -0.16), but was not maintained during follow-up. Hypertension control (< 140/90) in the practices improved by 5% during intervention (95% CI: 2.6%, 7.3%) and was sustained post-intervention 5.4% (95% CI: 2.6%, 8.2%).

conclusionsThe intervention failed to shorten follow-up time for patients with uncontrolled BP and showed very small, statistically significant improvements in SBP that were not sustained. However, the intervention showed statistically and clinically relevant improvement in hypertension control suggesting that the intervention affected clinician decision-making regarding BP control apart from visit frequency. Future practice initiatives should consider hypertension control as a primary outcome. CLINICAL TRIAL: www.ClinicalTrials.gov Identifier: NCT02164331.

Indexed as

Antihypertensive AgentsHypertensionAdultBlood PressureHumansAntihypertensive Agentsblood pressure controlclinical practice guidelinesCommunity Health Centers (CHCs)electronic health records (EHRs)Federally Qualified Health Centers (FQHCs)hypertensionpractice-based research networks (PBRNs)pragmatic trialsStepped Wedge Cluster Randomized Clinical Trial (SW-CRCT)

Identifiers

PMID34379277
PMCPMC8738829
OpenAlexW3192344058

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.