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ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2022

Jean-Martin Charcot (1825-1893) and the "Alice in Wonderland syndrome".

Francesco Brigo, Giorgio Zanchin, Mariano Martini, Lorenzo Lorusso, Study Group on the History of Neurology of the Italian Neurological Society

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Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francesco BrigoDepartment of Neurology, Hospital of Merano (SABES-ASDAA), Via Rossini, 5, 39012, Merano-Meran, Italy. dr.francescobrigo@gmail.com.ORCID http://orcid.org/0000-0003-0928-1577
Giorgio ZanchinDepartment of Neurosciences, University of Padua, Padova, Italy.
Mariano MartiniDepartment of Health Sciences, University of Genoa, Genoa, Italy.
Lorenzo LorussoUOC Neurology and Stroke Unit, ASST Lecco, Merate, Italy.
Study Group on the History of Neurology of the Italian Neurological Society

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The "Alice in Wonderland syndrome" (AIWS) is a neurological disorder characterized by altered body schema perception, visual, or somesthetic symptoms, which is frequently associated with migraine. In this article, we present the earliest known description of symptoms attributable to AIWS in the medical literature. During a lecture held on November 22, 1887, at the Salpêtrière, Jean-Martin Charcot (1825-1893) examined a patient with somesthetic symptoms (partial macrosomatognosia) in the context of migraine with aura. Although this condition was not known at the time, Charcot tried to provide an accurate semiological and nosographic framework of this case, attributing the complex of symptoms to migraine with aura and epilepsy with sensory symptoms. With intellectual honesty and clinical prudence, Charcot correctly pointed to a disturbance in the excitability of cortical areas responsible for processing and perceiving sensory stimuli.

Indexed as

Alice in Wonderland SyndromeMigraine DisordersHumansAlice in Wonderland syndromeHistory of medicineJean-Martin CharcotMacrosomatognosiaMigraineVisual aura

Identifiers

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.