ArticleWorld journal of microbiology & biotechnology2021
Photodynamic inactivation with curcumin and silver nanoparticles hinders Pseudomonas aeruginosa planktonic and biofilm formation: evaluation of glutathione peroxidase activity and ROS production.
Article in World journal of microbiology & biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Antibiotic Nanoparticles-Loaded Wound Dressings AgainstInternational journal of nanomedicine · 2024Pooled it
- Enhanced Antimicrobial Photodynamic Effect Against Escherichia coli Using MXene-Based Silver-Curcumin 2D Nanocomposite Photosensitizers.Journal of fluorescence · 2026Article
- Optimizing Silver Nanoparticle Properties: Synergistic Effects of Green Synthesis and Calcination on Crystallinity, Stability, and Bioactivity.Applied biochemistry and biotechnology · 2026Article
- Impact of protein corona and light modulation on the antibacterial activity of light-activated silver nanoparticles.Journal of materials chemistry. B · 2025Article
- Multi-omics driven biomarker discovery and pathological insights into Pseudomonas aeruginosa pneumonia.BMC infectious diseases · 2025Article
- A targeted and synergetic nano-delivery system againstMaterials today. Bio · 2025Article
- Light-Activable Silver Nanoparticles for Combatting Antibiotic-Resistant Bacteria and Biofilms.Molecules (Basel, Switzerland) · 2025Review
- Effect of Saponin on Methylene Blue (MB) Photo-Antimicrobial Activity Against Planktonic and Biofilm Form of Bacteria.Indian journal of microbiology · 2024Article
- Inhibitory effect of natural compounds on quorum sensing system inFrontiers in pharmacology · 2024Review
- Germicidal effect of intense pulsed light onFrontiers in microbiology · 2023Article
- Photo-responsive polymeric micelles for the light-triggered release of curcumin targeting antimicrobial activity.Frontiers in microbiology · 2023Article
- Influence of silver ion release on the inactivation of antibiotic resistant bacteria using light-activated silver nanoparticles.Materials advances · 2022Article
- Accelerating skin regeneration and wound healing by controlled ROS from photodynamic treatment.Inflammation and regeneration · 2022Review
- The Natural Product Curcumin as an Antibacterial Agent: Current Achievements and Problems.Antioxidants (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antibiotic-resistant bacteria result in high mortality in the world. Therefore, it is necessary to find new methods as alternative antibacterial agents that decline bacterial resistance and limit the spread of serious infectious bacterial diseases. Antimicrobial photodynamic therapy (aPDT) is a non-invasive strategy against antibiotic-resistant bacteria. aPDT contains the combination of non-toxic dyes with harmless visible light to create reactive oxygen species (ROS) that selectively lead to microbial cell death. Curcumin and silver nanoparticles (AgNPs) have antibacterial properties. In this study, the aPDT with curcumin plus AgNPs as photosensitizers on planktonic and biofilm forms of Pseudomonas aeruginosa was investigated. Also, the phototoxicity effect of curcumin and AgNPs on human fibroblast cells was studied. Finally, the ROS formation and the glutathione peroxidase (GPx) activity were evaluated. The results showed that the use of curcumin in combination with AgNPs then aPDT reduced the number of bacteria in planktonic and biofilm forms. Curcumin and AgNPs did not show any significant photocytotoxic effect against human normal fibroblast. Finally, the GPx activity was decreased in presence of curcumin in combination with AgNPs then aPDT compared to control. The ROS production in curcumin plus AgNPs then aPDT was higher than the control group. Therefore, curcumin-aPDT plus AgNPs could be suggested as novel strategies in treating multi-drug-resistant bacteria such as P. aeruginosa.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.