ArticleMicrobiology spectrum2021
Honeybee Exposure to Veterinary Drugs: How Is the Gut Microbiota Affected?
Article in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 43 citations in OpenAlex.
- Antimicrobial Resistance Genes (ARGs) Monitoring and Gut Microbiota Profiling in Honey Bees from an Intensive Livestock Farming Area in Northwestern Italy.Microorganisms · 2026Article
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- Hive-associated bacteria improve honeybee survival duringbioRxiv : the preprint server for biology · 2025Article
- Multi-Analyte Method for Antibiotic Residue Determination in Honey Under EU Regulation 2021/808.Antibiotics (Basel, Switzerland) · 2025Article
- Gut microbiome of Vespa orientalis: functional insights and potential honey bee pathogen dynamics.Animal microbiome · 2025Article
- Unintended consequences of antibiotic use in beekeeping: drone health as a potential vulnerability.Animal microbiome · 2025Article
- Antibiotic treatment of honey bee colonies alters early gut microbiome assembly and induces persistent dysbiosis in newly emerged workers.Scientific reports · 2025Article
- The Ground Beetle Poecilus (Carabidae) Gut Microbiome and Its Functionality.Microbial ecology · 2025Article
- Unravelling pollen diet and microbiome influence on honey bee health.Scientific reports · 2025Article
- PGPB administration influences the cross-talk and interactions of rhizosphere and endophyte microbial communities in sunflower.Current research in microbial sciences · 2025Article
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- EndophyticFrontiers in microbiology · 2025Article
- Article
- The Gut Microbiome of Two Wild Bumble Bee Species Native of South America: Bombus pauloensis and Bombus bellicosus.Microbial ecology · 2024Article
- Managing Microbiota Activity ofMicroorganisms · 2024Article
- The Bee Gut Microbiota: Bridging Infective Agents Potential in the One Health Context.International journal of molecular sciences · 2024Article
- The honeybee microbiota and its impact on health and disease.Nature reviews. Microbiology · 2024Review
- A longitudinal field study of commercial honey bees shows that non-native probiotics do not rescue antibiotic treatment, and are generally not beneficial.Scientific reports · 2024Article
- Article
- Alterations in the Microbiota of Caged Honeybees in the Presence of Nosema ceranae Infection and Related Changes in Functionality.Microbial ecology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several studies have outlined that a balanced gut microbiota offers metabolic and protective functions supporting honeybee health and performance. The present work contributes to increasing knowledge on the impact on the honeybee gut microbiota of the three most common veterinary drugs (oxytetracycline, sulfonamides, and tylosin). The study was designed with a semi-field approach in micro-hives containing about 500 honeybees. Micro-hives were located in an incubator during the day and moved outdoors in the late afternoon, considering the restrictions on the use of antibiotics in the open field but allowing a certain freedom to honeybees; 6 replicates were considered for each treatment. The absolute abundance of the major gut microbial taxa in newly eclosed individuals was studied with qPCR and next-generation sequencing. Antimicrobial resistance genes for the target antibiotics were also monitored using a qPCR approach. The results showed that the total amount of gut bacteria was not altered by antibiotic treatment, but qualitative variations were observed. Tylosin treatment determined a significant decrease of α- and β-diversity indices and a strong depletion of the rectum population (lactobacilli and bifidobacteria) while favoring the ileum microorganisms (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.