Evidence map›Paper›PMID 34378674›Full record

ArticleArquivos brasileiros de cardiologia2021

Performance of the Electrocardiogram in the Diagnosis of Left Ventricular Hypertrophy in Older and Very Older Hypertensive Patients.

Fernando Focaccia Povoa, Braulio Luna Filho, Henrique Tria Bianco, Celso Amodeo, Rui Povoa, Maria Teresa Nogueira Bombig, Roberto Dischinger Miranda, Simone Matheus Fischer, Maria Cristina Oliveira Izar, Francisco A H Fonseca

Open access · diamondAbstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Electrocardiographic Diagnosis of Left Ventricular Hypertrophy.Arquivos brasileiros de cardiologia · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Fernando Focaccia PovoaUniversidade Federal de São Paulo - Escola Paulista de Medicina, São Paulo, SP - Brasil.ORCID 0000-0002-9774-4406
Braulio Luna FilhoUniversidade Federal de São Paulo, São Paulo, SP - Brasil.
Henrique Tria BiancoUniversidade Federal de São Paulo - Escola Paulista de Medicina, São Paulo, SP - Brasil.ORCID 0000-0001-6746-8327
Celso AmodeoUniversidade Federal de São Paulo, São Paulo, SP - Brasil.
Rui PovoaUniversidade Federal de São Paulo, São Paulo, SP - Brasil.
Maria Teresa Nogueira BombigUniversidade Federal de São Paulo, São Paulo, SP - Brasil.ORCID 0000-0001-9603-6072
Roberto Dischinger MirandaUniversidade Federal de São Paulo - Escola Paulista de Medicina, São Paulo, SP - Brasil.ORCID 0000-0002-1582-7268
Simone Matheus FischerUniversidade Federal de São Paulo, São Paulo, SP - Brasil.
Maria Cristina Oliveira IzarUniversidade Federal de São Paulo, São Paulo, SP - Brasil.
Francisco A H FonsecaUniversidade Federal de São Paulo - Escola Paulista de Medicina, São Paulo, SP - Brasil.ORCID 0000-0002-9911-4598
Universidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft ventricular hypertrophy (LVH) is an important cardiovascular risk factor, regardless of arterial hypertension. Despite the evolution of imaging tests, the electrocardiogram (ECG) is still the most used in the initial evaluation, however, with low sensitivity.

objectiveTo evaluate the performance of the main electrocardiographic criteria for LVH in elderly and very elderly hypertensive individuals.

methodsIn a cohort of hypertensive patients, ECGs and doppler echocardiographies (ECHO) were performed and separated into three age groups: <60 years, Group I; 60-79 years Group II; and ≥80 years, Group III. The most used electrocardiographic criteria were applied for the diagnosis of LVH: Perugia; Pegaro-Lo Presti; Gubner-Ungerleider; Narita; (Rm+Sm) x duration; Cornell voltage; Cornell voltage duration; Sokolow-Lyon voltage; R of aVL ≥11 mm; RaVL duration. In evaluating the performance of these criteria, in addition to sensitivity (Sen) and specificity (Esp), the "Diagnostic Odds Ratios" (DOR) were analyzed. We considered p-value <0.05 for the analyses, with two-tailed tests.

resultsIn 2,458 patients, LVH was present by ECHO in 781 (31.7%). In Groups I and II, the best performances were for the criteria of Narita, Perugia, (Rm+Sm) x duration, with no statistical differences between them. In Group III (very elderly) the Perugia criteria and (Rm+Sm) x duration had the best performances: Perugia [44,7/89.3; (Sen/Esp)] and (Rm+Sm) duration [39.4%/91.3%; (Sen/Esp), p<0.05)], with the best PAIN results:6.8. This suggests that in this very elderly population, these criteria have greater discriminatory power to separate patients with LVH.

conclusionIn very elderly hypertensive patients, the Perugia electrocardiographic criteria and (Rm+Sm) x duration showed the best diagnostic performance for LVH.

Indexed as

HypertensionHypertrophy, Left VentricularAgedElectrocardiographyHumansMiddle AgedOdds RatioSensitivity and Specificity

Identifiers

PMID34378674
PMCPMC8682087
OpenAlexW3185221023

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.