ArticleJournal of attention disorders2022
Childhood Trajectories of Hyperactivity/Inattention Symptoms and Diurnal Cortisol in Middle Adolescence: Results from a UK Birth Cohort.
Article in Journal of attention disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- ADHD symptoms and diurnal cortisol in adolescents: The importance of comorbidities.Psychoneuroendocrinology · 2023Article
- A bidirectional Mendelian randomization study about the role of morning plasma cortisol in attention deficit hyperactivity disorder.Frontiers in psychiatry · 2023Article
- Temperament Dimensions and Awakening Cortisol Levels in Attention-Deficit/Hyperactivity Disorder.Frontiers in psychiatry · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveChildren with attention-deficit/hyperactivity disorder (ADHD) show hypoactivity of the hypothalamic-pituitary-adrenal (HPA) axis. Whether the association between hyperactivity/inattention symptoms with HPA axis dysfunction holds in the general child population too is not clear.
methodWe assessed associations between longitudinal trajectories of hyperactivity/inattention symptoms during ages 4 to 13 years and basal cortisol profiles at age 15 in a British general population cohort.
resultsAdolescents with persistently high levels of hyperactivity/inattention symptoms since childhood showed lower total morning cortisol and a smaller diurnal decline, even after adjusting for confounders. No associations were found between any of the symptom trajectories and cortisol awakening response, diurnal slope or daily output of cortisol.
conclusionThis study provides evidence for hypocortisolism among adolescents with chronic hyperactivity/inattention symptoms in the general population.
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Registered trials
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