Evidence map›Paper›PMID 34378235›Full record

ArticleBiometrical journal. Biometrische Zeitschrift2021

A statistical model for the dynamics of COVID-19 infections and their case detection ratio in 2020.

Marc Schneble, Giacomo De Nicola, Göran Kauermann, Ursula Berger

Abstract read
In one paragraph

Article in Biometrical journal. Biometrische Zeitschrift, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Advancing Precision Vaccinology by Molecular and Genomic Surveillance of Severe Acute Respiratory Syndrome Coronavirus 2 in Germany, 2021.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  7. Article
  8. Estimating COVID-19-induced excess mortality in Lombardy, Italy.Aging clinical and experimental research · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marc SchnebleDepartment of Statistics, LMU Munich, Munich, Germany.ORCID 0000-0001-9523-4173
Giacomo De NicolaDepartment of Statistics, LMU Munich, Munich, Germany.
Göran KauermannDepartment of Statistics, LMU Munich, Munich, Germany.
Ursula BergerInstitute for Medical Information Processing, Biometry and Epidemiology, LMU Munich, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The case detection ratio of coronavirus disease 2019 (COVID-19) infections varies over time due to changing testing capacities, different testing strategies, and the evolving underlying number of infections itself. This note shows a way of quantifying these dynamics by jointly modeling the reported number of detected COVID-19 infections with nonfatal and fatal outcomes. The proposed methodology also allows to explore the temporal development of the actual number of infections, both detected and undetected, thereby shedding light on the infection dynamics. We exemplify our approach by analyzing German data from 2020, making only use of data available since the beginning of the pandemic. Our modeling approach can be used to quantify the effect of different testing strategies, visualize the dynamics in the case detection ratio over time, and obtain information about the underlying true infection numbers, thus enabling us to get a clearer picture of the course of the COVID-19 pandemic in 2020.

Indexed as

COVID-19PandemicsHumansModels, StatisticalSARS-CoV-2case detection ratioCOVID-19dark figure of infectionsgeneralized additive modelspenalized splines

Identifiers

PMID34378235
PMCPMC8426968

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.