Evidence map›Paper›PMID 34378199›Full record

Trial reportClinical cardiology2021

An echocardiographic model for predicting the recurrence of paroxysmal atrial fibrillation after circumferential pulmonary vein ablation.

Yuxia Miao, Min Xu, Chunxu Zhang, Huannian Liu, Xiaoliang Shao, Yuetao Wang, Junhua Yang

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yuxia MiaoDepartment of Cardiovascular, Division of The Third Affiliated Hospital of Soochow University, Chang Zhou City, China.ORCID https://orcid.org/0000-0001-9050-7128
Min XuDepartment of Cardiovascular, Division of The Third Affiliated Hospital of Soochow University, Chang Zhou City, China.
Chunxu ZhangDepartment of Cardiovascular, Division of Changzhou Municipal Hospital of Traditional Chinese Medicine, Chang Zhou City, China.
Huannian LiuDepartment of Cardiovascular, Division of Changzhou Cancer Hospital Affiliated to Soochow University, Chang Zhou City, China.
Xiaoliang ShaoDepartment of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Chang Zhou City, China.
Yuetao WangDepartment of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Chang Zhou City, China.
Junhua YangDepartment of Cardiovascular, Division of The First Affiliated Hospital of Soochow University, Su Zhou City, China.
Soochow University · CNHangzhou Hospital of Traditional Chinese Medicine · CN

Funding

Changzhou City Health Bureau WZ201804Changzhou City Technology Bureau CJ20190086National Natural Science Foundation of China 81471690
6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) is a highly prevalent arrhythmia, with substantial associated morbidity and mortality. Circumferential pulmonary vein ablation (CPVA) is an effective rhythm control strategy, however, recurrence is an important factor influencing treatment decisions. HYPOTHESIS: To develop a predictive model based on left atrial (LA) structure and function, and evaluate its efficiency in predicting the recurrence of AF after CPVA.

methodsPatients with paroxysmal AF who underwent CPVA were enrolled in this study and randomly divided into a development set and a validation set. The clinical and echocardiographic data of each patient were collected. In the development set, a least absolute shrinkage and selection operator (LASSO) regression was used to establish a LA ultrasound feature. By combining that LA ultrasound feature with independent clinical risk factors, we established an echocardiographic model using multivariate logistic regression and plotted the corresponding nomogram.

resultsThe LA ultrasound feature established by LASSO regression included nine echocardiographic indicators related to LA structure and function. It also exhibited good predictive ability in both the development set and the validation set (AUC:0.944, 95%CI: 0.910-0.978; AUC:0.878, 95%CI: 0.816-0.942). Logistic regression analysis indicated that LA ultrasound feature and AF duration were independent predictors for AF recurrence. The combined model including LA ultrasound feature and AF duration also showed good discriminability in both the development set (AUC: 0.950, 95% CI:0.914-0.985) and the validation set (AUC: 0.890, 95% CI: 0.831-0.949). The calibration curve showed good agreement between the predicted value and observed value.

conclusionsOur model that is based on LA structure and function measured by echocardiography is a useful non-invasive preoperative tool, which exhibits good accuracy in predicting the recurrence of AF after CPVA.

Indexed as

Atrial FibrillationCatheter AblationPulmonary VeinsEchocardiographyHeart AtriaHumansRecurrenceTreatment Outcomecatheter ablationleft atriumparoxysmal atrial fibrillationrecurrence

Identifiers

PMID34378199
PMCPMC8571557
OpenAlexW3191682166

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.