Evidence map›Paper›PMID 34378140›Full record

ReviewJournal of molecular neuroscience : MN2021

Role of circRNAs in neurodevelopment and neurodegenerative diseases.

Junwei Li, Chenyou Sun, Huairui Cui, Jinhao Sun, Peng Zhou

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of molecular neuroscience : MN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
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  15. Circular RNAs: emerging players in asthma and COPD.Frontiers in cell and developmental biology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Junwei LiDepartment of Anatomy, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Chenyou SunDepartment of Anatomy, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Huairui CuiDepartment of Anatomy, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Jinhao SunDepartment of Anatomy, School of Basic Medical Sciences, Shandong University, Jinan, Shandong, China.
Peng ZhouDepartment of Anatomy, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China. zxnp8888@163.com.ORCID http://orcid.org/0000-0001-6415-3581
Wenzhou Medical University · CNShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the rapid development of sequencing technology, scientists have been able to study and acquire a better understanding of non-coding RNAs (ncRNAs). Circular RNAs (circRNAs), a unique class of ncRNAs with a special loop structure, have been found to possess modulatory properties with respect to various biological processes, such as interacting with nucleic acids or proteins. In addition to their tissue-specific expression and high conservation across species, circRNAs are abundant and dynamically expressed in the nervous system, especially in nerve synapse, indicating their potential regulation in synaptic plasticity or neuronal disorders. In this review, we discuss the characteristics of circRNAs and their common biological functions, as well as their significant role in neurodevelopment, drug addiction and neurodegenerative diseases, aiming to guide further disease diagnoses and efficient therapy.

Indexed as

NeurogenesisAnimalsHumansNeurodegenerative DiseasesRNA, CircularRNA, CircularBiological functionCharacteristicscircRNAsNeurodegenerative diseasesNeurodevelopment

Identifiers

PMID34378140
OpenAlexW3188364914

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.