Evidence map›Paper›PMID 34378113›Full record

ArticleJournal of general internal medicine2022

Associations Between Industry Payments to Physicians for Antiplatelet Drugs and Utilization of Cardiac Procedures and Stents.

Mao Yanagisawa, Daniel M Blumenthal, Hirotaka Kato, Kosuke Inoue, Yusuke Tsugawa

Open access · hybridAbstract read
In one paragraph

Article in Journal of general internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Mao YanagisawaDivision of General Internal Medicine and Health Services Research, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. mao.yanagisawa@outlook.com.
Daniel M BlumenthalCardiology Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Hirotaka KatoDivision of General Internal Medicine and Health Services Research, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Kosuke InoueDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, USA.
Yusuke TsugawaDivision of General Internal Medicine and Health Services Research, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.ORCID 0000-0002-1937-4833
University of California, Los Angeles · USHarvard University · USUCLA Health · US

Funding

The Impact of Surgeon Factors and Education/Training on Disparities in Surgical Care.R01MD013913 · NIMHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TSUGAWA, YUSUKE · 2020 to 2024
$3.6M
The Impact of physician and health system factors on the quality of care for persons with Alzheimer's disease and related dementias at the end of lifeR01AG068633 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TSUGAWA, YUSUKE · 2020 to 2024
$3.0M
Effects of Chronic Kidney Disease on Cardiovascular Disease and Dementia Among People with Diabetes: Causal Modeling with Machine Learning ApproachF99DK126119 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI INOUE, KOSUKE · 2020 to 2020
$34k
NIA NIH HHS R01 AG068633NIDDK NIH HHS F99 DK126119NIMHD NIH HHS R01 MD013913
6 · The paper itself

Abstract

backgroundA study has shown that industry payments to physicians for drugs are associated not only with higher drug prescriptions but also with higher non-drug costs due to additional utilization of healthcare services. However, the association between industry payments to cardiologists for antiplatelet drugs and the costs and number of percutaneous coronary interventions they perform has not been investigated.

objectiveTo examine the association between industry payments to cardiologists for antiplatelet drugs and the costs and number of percutaneous coronary interventions they perform.

designUsing the 2016 Open Payments Database linked to the 2017 Medicare Provider Utilization and Payment Data, we examined the association between the value of industry payments related to the antiplatelet drugs prasugrel and ticagrelor and healthcare spending and volume for cardiovascular procedures, adjusted for potential cofounders. SUBJECTS: A total of 7456 cardiologists who performed diagnostic cardiac catheterizations on Medicare beneficiaries in 2017. MAIN MEASURES: Primary outcomes included (1) healthcare spending on cardiac procedures, (2) diagnostic cardiac catheterization volumes, and (3) rates of coronary stenting. Secondary outcomes were total expenditures for all drugs and for antiplatelet drugs. KEY

resultsIndustry payments for antiplatelet drugs were associated with higher healthcare spending on cardiac procedures (adjusted difference, +$50.9 for additional $100 industry payments; 95% CI, +$25.5 to +$76.2; P < 0.001), diagnostic cardiac catheterizations (+0.1 procedures per cardiologist; 95% CI, +0.03 to +0.1; P=0.001), and stent use (+0.5 per 1000 diagnostic cardiac catheterizations per cardiologist; 95% CI, +0.2 to +0.9; P=0.002). Industry payments for antiplatelet drugs were associated with higher total costs for all drugs and antiplatelet drugs.

conclusionsIndustry payments to cardiologists for antiplatelet drugs were associated with both prescribing of antiplatelet drugs and the use of cardiac procedures and stents. Further research is warranted to understand whether the observed associations are causal or reflect a greater propensity for higher volume proceduralists to have relationships with industry.

Indexed as

Medicare Part DPhysiciansPrescription DrugsAgedDrug IndustryHumansPlatelet Aggregation InhibitorsPractice Patterns, Physicians'StentsUnited StatesPlatelet Aggregation InhibitorsPrescription Drugs

Identifiers

PMID34378113
PMCPMC9130441
OpenAlexW3187792309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.