Evidence map›Paper›PMID 34378103›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2021

Ruthenium-based PACT agents based on bisquinoline chelates: synthesis, photochemistry, and cytotoxicity.

Anja Busemann, Ingrid Flaspohler, Xue-Quan Zhou, Claudia Schmidt, Sina K Goetzfried, Vincent H S van Rixel, Ingo Ott, Maxime A Siegler, Sylvestre Bonnet

Open access · hybridAbstract read
In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. RuBi-Ruxolitinib: A Photoreleasable Antitumor JAK Inhibitor.Journal of the American Chemical Society · 2024
    Article
  8. Article
  9. Ruthenium-Based Photoactivated Chemotherapy.Journal of the American Chemical Society · 2023
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Anja BusemannLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333CC, Leiden, The Netherlands.
Ingrid FlaspohlerLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333CC, Leiden, The Netherlands.
Xue-Quan ZhouLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333CC, Leiden, The Netherlands.
Claudia SchmidtInstitute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, Beethovenstrasse 55, 38106, Braunschweig, Germany.ORCID https://orcid.org/0000-0001-8532-2604
Sina K GoetzfriedLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333CC, Leiden, The Netherlands.
Vincent H S van RixelLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333CC, Leiden, The Netherlands.
Ingo OttInstitute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, Beethovenstrasse 55, 38106, Braunschweig, Germany.ORCID https://orcid.org/0000-0002-8087-4618
Maxime A SieglerSmall Molecule X-Ray Facility, Department of Chemistry, Johns Hopkins University, Baltimore, Maryland, 21218, USA.
Sylvestre BonnetLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333CC, Leiden, The Netherlands. bonnet@chem.leidenuniv.nl.ORCID http://orcid.org/0000-0002-5810-3657
Leiden University · NLTechnische Universität Braunschweig · DEJohns Hopkins University · US

Funding

European Research Council Starting Grant
6 · The paper itself

Abstract

The known ruthenium complex [Ru(tpy)(bpy)(Hmte)](PF

Indexed as

Antineoplastic AgentsCell Line, TumorCell SurvivalHumansModels, MolecularMolecular StructureRutheniumRuthenium CompoundsAntineoplastic AgentsRutheniumRuthenium Compounds

Identifiers

PMID34378103
PMCPMC8437835
OpenAlexW3190904588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.