ReviewMaterials today. Bio2021
Mesoporous bioactive glasses for regenerative medicine.
Review in Materials today. Bio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 128 citations in OpenAlex.
- Bioactive glasses-mediated ion therapy ameliorates hepatic osteodystrophy by reprogramming the liver-bone axis.Bioactive materials · 2027Article
- Biopolymer-mediated metallic nanomaterials: recent advancements, current challenges and future outlooks.RSC advances · 2026Review
- From bone replacement to regeneration. A biomaterials started journey.Materials today. Bio · 2026Review
- An immunomodulatory bioactive glass orchestrates early bone healing via coordinated macrophage polarization and osteogenesis-osteolysis balance.Materials today. Bio · 2026Article
- Mesoporous Bioactive Glass: Preparation, Characterisation, and Emerging Applications in Regenerative Medicine and Dentistry.International dental journal · 2026Review
- Article
- Recent advances in biomaterials for bone regeneration: Bridging innovation and clinical translation.Materials today. Bio · 2026Review
- Shedding Light on the Cellular Uptake Mechanisms of Bioactive Glass Nanoparticles as Controlled Intracellular Delivery Platforms: A Review of the Recent Literature.Advanced healthcare materials · 2026Review
- Macrophage polarisation under immune regulation as a therapeutic target for tendon-bone healing: multifactorial regulation and mechanistic insights.Frontiers in immunology · 2026Review
- Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery.Advanced healthcare materials · 2026Review
- Mesoporous bioactive glass-recombinant collagen III nanocomposite capsule promotes skin wound healing via adaptive immune modulation.Regenerative biomaterials · 2026Article
- Three-Dimensional Printing of Calcium Phosphate-Mesoporous Bioactive Glass Scaffolds for Bone Tissue Engineering.Journal of functional biomaterials · 2025Article
- Hierarchically porous copper and gallium loaded sol-gel phosphate glasses for enhancement of wound closure.Journal of materials chemistry. B · 2025Article
- Tannic acid-loaded zinc- and copper-doped mesoporous bioactive glass nanoparticles: Potential antioxidant nanocarriers for wound healing.Bioactive materials · 2025Article
- Determination of Biochemical and Metabolomic Characteristics of Sheep Blood Serum and Their Application in Clinical Practice.Life (Basel, Switzerland) · 2025Article
- From hard tissues to beyond: Progress and challenges of strontium-containing biomaterials in regenerative medicine applications.Bioactive materials · 2025Review
- L-arginine modified mesoporous bioactive glass with ROS scavenging and NO release for periodontitis treatment.Bioactive materials · 2025Article
- Balanced enhancement of antibacterial activity and biocompatibility in chitosan-vancomycin 3D-printed scaffolds through mesoporous bioactive glass addition.Journal of drug delivery science and technology · 2025Article
- Metal-organic framework (MOF)-bioactive glass (BG) systems for biomedical applications - A review.Materials today. Bio · 2025Review
- Plant Resin Delivery by Nanovectors as an Emerging Approach to Boost Solubility, Permeability and Bioavailability.Pharmaceutics · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stem cells are the central element of regenerative medicine (RM). However, in many clinical applications, the use of scaffolds fabricated with biomaterials is required. In this sense, mesoporous bioactive glasses (MBGs) are going to play an important role in bone regeneration because of their striking textural properties, quick bioactive response, and biocompatibility. As other bioactive glasses, MBGs are mainly formed by silicon, calcium, and phosphorus oxides whose ions play an important role in cell proliferation as well as in homeostasis and bone remodeling process. A common improvement of bioactive glasses for RM is by adding small amounts of oxides of elements that confer them additional biological capacities, including osteogenic, angiogenic, antibacterial, anti-inflammatory, hemostatic, or anticancer properties. Moreover, MBGs are versatile in terms of the different ways in which they can be processed, such as scaffolds, fibers, coatings, or nanoparticles. MBGs are unique because their textural properties are so high that they still exhibit outstanding bioactive responses even after adding extra inorganic ions or being processed as scaffolds or nanoparticles. Moreover, they can be further improved by loading with biomolecules, drugs, and stem cells. This article reviews the state of the art and future perspectives of MBGs in the field of RM of hard tissues.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.