Evidence map›Paper›PMID 34377929›Full record

ArticleTherapeutic advances in vaccines and immunotherapy2021

Pregnant women's hepatitis B vaccination coverage in Nigeria: a national pilot cross-sectional study.

George Uchenna Eleje, Godwin Otuodichinma Akaba, Ikechukwu Innocent Mbachu, Ayyuba Rabiu, Olabisi Morebise Loto, Hadiza Abdullahi Usman, Preye Owen Fiebai, Rebecca Chinyelu Chukwuanukwu, Ngozi Nneka Joe-Ikechebelu, Chike Henry Nwankwo and 32 more

Abstract read
In one paragraph

Article in Therapeutic advances in vaccines and immunotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors.

George Uchenna ElejeEffective Care Research Unit, Department of Obstetrics and Gynecology, Faculty of Medicine, Nnamdi Azikiwe University, Awka, Nigeria.ORCID https://orcid.org/0000-0002-0390-2152
Godwin Otuodichinma AkabaDepartment of Obstetrics and Gynecology, University of Abuja, Abuja, Nigeria.
Ikechukwu Innocent MbachuDepartment of Obstetrics and Gynecology, Nnamdi Azikiwe University, Awka, Nigeria.
Ayyuba RabiuDepartment of Obstetrics and Gynecology, Bayero University, Kano, Nigeria.
Olabisi Morebise LotoDepartment of Obstetrics and Gynecology, Obafemi Awolowo University, Ile-Ife, Nigeria.
Hadiza Abdullahi UsmanDepartment of Obstetrics and Gynecology, University of Maiduguri, Maiduguri, Nigeria.
Preye Owen FiebaiDepartment of Obstetrics and Gynecology, University of Port Harcourt, Port Harcourt, Nigeria.
Rebecca Chinyelu ChukwuanukwuImmunology Unit, Department of Medical Laboratory Science, Nnamdi Azikiwe University, Awka, Nigeria.
Ngozi Nneka Joe-IkechebeluDepartment of Community Medicine, Chukwuemeka Odumegwu Ojukwu University Teaching Hospital, Awka, Nigeria.
Chike Henry NwankwoDepartment of Statistics, Nnamdi Azikiwe University, Awka, Nigeria.
Stephen Okoroafor KaluHIV Care Laboratory/HIV Care Department, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.
Chinyere Ukamaka OnuboguDepartment of Paediatrics, Nnamdi Azikiwe University, Awka, Nigeria.
Chukwuanugo Nkemakonam OgbuaguDepartment of Medical Microbiology and Parasitology, Faculty of Medicine, Nnamdi Azikiwe University, Awka, Nigeria.
Shirley Nneka ChukwurahGastroenterology Unit, Department of Medicine, Faculty of Medicine, Nnamdi Azikiwe University, Awka, Nigeria.
Chinwe Elizabeth UzochukwuDepartment of Mass Communication, Nnamdi Azikiwe University, Awka, Nigeria.
Samuel Oluwagbenga InuyomiDepartment of Physics and Engineering Physics, Obafemi Awolowo University, Ile-Ife, Nigeria.
Bukola Abimbola AdesojiDepartment of Nursing, Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife, Nigeria.
Uchenna Chukwunonso OgwaluonyeDepartment of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Nigeria.
Sussan Ifeyinwa NwejeDepartment of Nursing, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.
Richard Obinwanne EgeonuDepartment of Obstetrics and Gynecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria.
Odion Emmanuel IgueDepartment of Physiological Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.
Chiamaka Henrietta JibuakuDepartment of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Nigeria.
Prince Ogbonnia AjaImmunology Unit, Department of Medical Laboratory Science, Nnamdi Azikiwe University, Awka, Nigeria.
Chiamaka Perpetua ChidozieImmunology Unit, Department of Medical Laboratory Science, Nnamdi Azikiwe University, Awka, Nigeria.
Hadiza Sani IbrahimDepartment of Obstetrics and Gynecology, Aminu Kano Teaching Hospital, Kano, Nigeria.
Fatima Ele AliyuDepartment of Obstetrics and Gynecology, Aminu Kano Teaching Hospital, Kano, Nigeria.
Aisha Ismaila NumanDepartment of Obstetrics and Gynecology, University of Maiduguri Teaching Hospital, Maiduguri, Nigeria.
Ogbonna Dennis OkoroDepartment of Parasitology & Entomology, Faculty of Veterinary Medicine, University of Maiduguri, Maiduguri, Borno State, Nigeria.
Solace Amechi OmoruyiDepartment of Obstetrics and Gynecology, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.
Ijeoma Chioma OppahDepartment of Obstetrics and Gynecology, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.
Ubong Inyang AnyangDepartment of Obstetrics and Gynecology, University of Abuja Teaching Hospital, Abuja, Nigeria.
Aishat AhmedDepartment of Obstetrics and Gynecology, University of Abuja Teaching Hospital, Abuja, Nigeria.
Osita Samuel UmeononihuDepartment of Obstetrics and Gynecology, Nnamdi Azikiwe University, Awka, Nigeria.
Eric Okechukwu UmehDepartment of Radiology, Faculty of Medicine, Nnamdi Azikiwe University, Awka, Nigeria.
Ekene Agatha EmekaDepartment of Family Medicine, Faculty of Medicine, Nnamdi Azikiwe University, Awka, Nigeria.
Arinze Anthony OnwuegbunaDepartment of Ophthalmology, Nnamdi Azikiwe University, Awka, Nigeria.
Emeka Philip IgbodikeDepartment of Obstetrics and Gynecology, St Georges Hospital Memorial Centre, Lagos, Nigeria.
Ifeoma Clara AjubaDepartment of Hematology, Faculty of Medicine, Nnamdi Azikiwe University, Awka, Nigeria.
Ibrahim Adamu YakasaiDepartment of Obstetrics and Gynecology, Bayero University, Kano, Nigeria.
Oliver Chukwujekwu EzechiNigerian Institute of Medical Research, Lagos, Nigeria.
Joseph Ifeanyichukwu IkechebeluDepartment of Obstetrics and Gynecology, Nnamdi Azikiwe University, Awka, Nigeria.
Triplex Infection in Pregnancy Collaboration Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the hepatitis B vaccination coverage, full-dose (⩾3) coverage and the associated factors affecting uptake among pregnant women.

methodsThis was a cross-sectional study among pregnant women attending antenatal care in six tertiary hospitals across all the geopolitical zones of Nigeria. Pregnant women who consented to the study completed screening questions about their hepatitis B vaccination status and coverage. The main outcome measures were hepatitis B vaccination coverage rate, dose, and factors affecting uptake. Bivariate analysis was performed by the chi-square test and conditional logistic regression analysis was used to determine variables associated with uptake of the vaccination. Odds ratios (ORs) and adjusted odds ratios (aORs) were calculated and statistical significance was accepted when

resultsOf 159 pregnant women who completed the interview questions, 21 [13.2%, 95% confidence interval (CI) 7.9-18.5%] were vaccinated for hepatitis B for one to three doses. The numbers of doses received were: three doses (8/159, 5.0%), two doses (5/159, 3.1%), and one dose (8/159, 5.0%). The reasons for non-uptake of vaccination included: lack of awareness of the vaccine 83/138 (60.1%), inadequate access to vaccine 11/138 (8.0%), and positivity to hepatitis B virus 10/138 (7.2%). The uptake of hepatitis B vaccination was significantly affected by the level of education (OR 0.284, 95% CI 0.08-1.01,

conclusionsIn Nigeria, the national hepatitis B vaccination coverage among pregnant women appears poor, with the full-dose coverage even poorer. The level of education was not positively associated with uptake of hepatitis B vaccination, while lack of awareness of the vaccine was the commonest reason for non-uptake.

fundingTETFund National Research Fund 2019 (grant number TETFund/DR&D/CE/NRF/STI/33).

Indexed as

antenatal carecoveragehepatitis Bpregnancyvaccinationvirus

Identifiers

PMID34377929
PMCPMC8327013

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.