Evidence map›Paper›PMID 34377838›Full record

ArticleBiology methods & protocols2021

Quantifying the invasion and migration ability of cancer cells with a 3D Matrigel drop invasion assay.

Merve Aslan, En-Chi Hsu, Shiqin Liu, Tanya Stoyanova

Open access · goldAbstract read
In one paragraph

Article in Biology methods & protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  6. Review
  7. Archives of medical science : AMS · 2026
    Article
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  16. Oncology letters · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Merve AslanDepartment of Radiology, Canary Center at Stanford for Cancer Early Detection, Stanford University, 3155 Porter Drive. Palo Alto, CA 94304, USA.
En-Chi HsuDepartment of Radiology, Canary Center at Stanford for Cancer Early Detection, Stanford University, 3155 Porter Drive. Palo Alto, CA 94304, USA.
Shiqin LiuDepartment of Radiology, Canary Center at Stanford for Cancer Early Detection, Stanford University, 3155 Porter Drive. Palo Alto, CA 94304, USA.
Tanya StoyanovaDepartment of Radiology, Canary Center at Stanford for Cancer Early Detection, Stanford University, 3155 Porter Drive. Palo Alto, CA 94304, USA.ORCID https://orcid.org/0000-0003-0119-9747
Stanford University · US

Funding

Elucidating the Role of Trop2 in Prostate CancerR37CA240822 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Tanya I Stoyanova · 2020 to 2026
$2.5M
Elucidating the Role of UCHL1 in Aggressive Prostate CancerR01CA244281 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI STOYANOVA, TANYA I · 2020 to 2024
$1.8M
Celigo S Imaging Cytometer (200-BFFL-S)S10OD023518 · OD · STANFORD UNIVERSITY · PI PAULMURUGAN, RAMASAMY · 2018 to 2018
$174k
NCI NIH HHS R01 CA244281NCI NIH HHS R37 CA240822NIH HHS S10 OD023518
6 · The paper itself

Abstract

Metastasis is the main cause of cancer-associated morbidity which will account for ∼ 600,000 deaths in the USA in 2021. Defining new mechanisms that drive cancer metastasis is vital for developing new therapeutic strategies and improving clinical outcomes for cancer patients. Herein, we describe a recently established 3D Matrigel drop invasion assay to measure cancer cell invasion and migration capability

Indexed as

cancermetastasismigration

Identifiers

PMID34377838
PMCPMC8346651
OpenAlexW3192339688

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.