Evidence map›Paper›PMID 34377729›Full record

ArticleOpen forum infectious diseases2021

Updated Experience of

Nicholas Y Tan, Alex D Tarabochia, Daniel C DeSimone, Christopher V DeSimone, John W Wilson, Gabor Bagameri, Courtney E Bennett, Omar M Abu Saleh

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. DisseminatedASM case reports · 2026
    Article
  2. Multimodal Imaging inMayo Clinic proceedings. Innovations, quality & outcomes · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Pharmacologic Management ofOpen forum infectious diseases · 2022
    Review
  8. Proceedings (Baylor University. Medical Center) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nicholas Y TanDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Alex D TarabochiaDivision of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Daniel C DeSimoneDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Christopher V DeSimoneDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
John W WilsonDepartment of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA.
Gabor BagameriDepartment of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Courtney E BennettDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Omar M Abu SalehDepartment of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0003-4955-5544
Mayo Clinic · USMayo Clinic in Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite safety communications from the Food and Drug Administration (FDA) regarding the outbreak of

methodsWe retrospectively reviewed confirmed cases of MCI that were managed at Mayo Clinic sites (Arizona, Florida, and Minnesota) from 09/2015 to 01/2021. Clinical histories including prior cardiovascular surgery were recorded. Diagnostic workup including ophthalmologic examination, imaging, and laboratory testing was reviewed. Treatment and survival outcomes on follow-up were obtained.

resultsTwelve patients with MCI were included. All patients had aortic valve or graft replacement. Five patients had their surgical procedures following the 10/15/2015 FDA safety communication. The mean time from surgery to symptom onset (range) was 32 (13-73) months. Ten of 11 patients who underwent ophthalmologic examination had chorioretinal abnormalities. Three patients who underwent microbial cell-free deoxyribonucleic acid sequencing tested positive for

conclusionsMCI continues to occur despite the FDA communications. Incorporation of ophthalmologic examination and use of advanced tools may improve MCI diagnosis. The mortality in these patients is high even with aggressive surgical/medical management.

Indexed as

cardiovascular surgeryMycobacterium chimaeranontuberculous mycobacteriumprosthetic valve endocarditis

Identifiers

PMID34377729
PMCPMC8339283
OpenAlexW3182757827

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.