Evidence map›Paper›PMID 34377679›Full record

ArticleToxicology reports2021

Risk factors associated with COVID-19-induced death in patients hospitalized in intensive care units (ICUs) in a city in Southern Brazil.

André S Olak, Aline M Susuki, Milena Kanashiro, Monica M B Paoliello, Michael Aschner, Mariana R Urbano

RetractedAbstract read
In one paragraph

Article in Toxicology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

  • Expression of concern · 2021-12-17Concerns/Issues about Data · Concerns/Issues about Results and/or Conclusions · Investigation by Journal/Publisher · · the entire special issue is subject to an expression of concern;
  • Expression of concern · 2021-12-17Concerns/Issues about Data · Concerns/Issues about Results and/or Conclusions · Investigation by Journal/Publisher · · the entire special issue is subject to an expression of concern;
5 · Who and what money

Authors and funding

6 authors.

André S OlakDepartment of Statistics, State University of Londrina (UEL), Londrina, PR, Brazil.
Aline M SusukiDepartment of Architecture and Urbanism, State University of Londrina (UEL), Londrina, PR, Brazil.
Milena KanashiroDepartment of Architecture and Urbanism, State University of Londrina (UEL), Londrina, PR, Brazil.
Monica M B PaolielloDepartment of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA.
Michael AschnerDepartment of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA.
Mariana R UrbanoDepartment of Statistics, State University of Londrina (UEL), Londrina, PR, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this research was to address risk factors associated with death after hospitalization in intensive care units (ICUs) in 728 COVID-19 patients in Londrina, the second most populated city in the State of Paraná - Brazil, between March and December 2020.

methodsStatistical analysis, including multiple logistic regression was performed to identify risk factors associated with death in these patients.

resultsThe results showed that age (60 years or more, O.R. = 3.13, C.I. 95% [2.02; 4.84]), days in the ICU (11 days or more, O.R. = 1.76, C.I. 95% [1.16; 2.66]), neurological diseases (O.R. = 2.15, C.I. 95% [1.07; 4.31]), pneumopathy (O.R = 2.19, C.I. 95% [1.01; 4.82]), diabetes (O.R. = 1.55, C.I. 95% [1.03; 2.32]), and kidney disease (O.R. = 2.27, C.I. 95% [1.18; 4.70]) were associated with increased risk for death from COVID-19.

conclusionKnowing the risk factors associated with death after ICUs hospitalization is useful for identifying the most vulnerable groups, as well as for defining vaccination priorities, considering its scarcity in many parts of the world, mainly in underdeveloped countries, including Brazil.

Indexed as

COVID-19PandemicRisk factorsStatistical analysis

Identifiers

PMID34377679
PMCPMC8340553

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.