Evidence map›Paper›PMID 34377581›Full record

ReviewaBIOTECH2021

Engineering

Jianing Han, Yinan Wu, Yilun Zhou, Sijin Li

Open access · bronzeAbstract readReview
In one paragraph

Review in aBIOTECH, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Cutting-edge plant natural product pathway elucidation.Current opinion in biotechnology · 2024
    Review
  5. Article
  6. Biosynthesis of tetrahydropapaverine and semisynthesis of papaverine in yeast.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. Metabolic engineering communications · 2022
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jianing HanRobert Frederick Smith School of Chemical and Biomolecular Engineering, 230A Olin Hall, Cornell University, Ithaca, NY 14853 USA.
Yinan WuRobert Frederick Smith School of Chemical and Biomolecular Engineering, 230A Olin Hall, Cornell University, Ithaca, NY 14853 USA.
Yilun ZhouRobert Frederick Smith School of Chemical and Biomolecular Engineering, 230A Olin Hall, Cornell University, Ithaca, NY 14853 USA.
Sijin LiRobert Frederick Smith School of Chemical and Biomolecular Engineering, 230A Olin Hall, Cornell University, Ithaca, NY 14853 USA.ORCID 0000-0003-0364-5632
Cornell University · US

Funding

Simultaneous Treatment of Viral and Bacterial Otitis Media Using Plant Natural ProductsR21DC019206 · NIDCD · CORNELL UNIVERSITY · PI LI, SIJIN · 2021 to 2023
$441k
NIDCD NIH HHS R21 DC019206
6 · The paper itself

Abstract

Benzylisoquinoline alkaloids (BIAs) are a diverse family of plant natural products with extensive pharmacological properties, but the yield of BIAs from plant is limited. The understanding of BIA biosynthetic mechanism in plant and the development of synthetic biology enable the possibility to produce BIAs through microbial fermentation, as an alternative to agriculture-based supply chains. In this review, we discussed the engineering strategies to synthesize BIAs in

Indexed as

Benzylisoquinoline alkaloids (BIAs)Metabolic engineeringSaccharomyces cerevisiaeSynthetic biology

Identifiers

PMID34377581
PMCPMC8286646
OpenAlexW3186084512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.