ReviewSAGE open medicine2021
In-hospital mortality and its predictors among stroke patients in sub-Saharan Africa: A systemic review and meta-analysis.
Review in SAGE open medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Stroke risk factors and outcomes in Trinidad and Tobago: the START study.BMC neurology · 2026Observational
- Stroke in Sierra Leone: Insights From a Retrospective Review to Support the Development of a Neurosurgical Department in the Country.Neurosurgery practice · 2026Article
- Post-Stroke Limitations on Activities of Daily Living and Associated Factors in Public Tertiary Hospitals in Amhara Regional State, Ethiopia: A Multicenter Cross-Sectional Study.Health science reports · 2026Article
- Epidemiological and clinical profile of ischemic, hemorrhagic, and mixed strokes in Sikasso, Mali: a prospective cross-sectional study.The Pan African medical journal · 2026Article
- Spatial distribution of mortality: evidence from DIMAMO HDSS, Limpopo Province, South Africa.BMC public health · 2025Article
- Mortality rate of stroke and its determinants in Africa: An umbrella review of systematic review and meta-analysis.Global epidemiology · 2025Review
- Demographic Disparities in Stroke Occurrence: Insights From an Integrative Review of Emerging Trends.Brain and behavior · 2025Review
- Characterizing stroke presenting to a regional referral hospital before and during the COVID-19 pandemic in Uganda: a retrospective analysis.International journal of emergency medicine · 2025Article
- Impact of diabetes mellitus on 30-day mortality among acute stroke patients in northern Tanzania.PloS one · 2025Article
- Mortality rate and predictors among stroke patients in the public hospitals in Harari region, Eastern Ethiopia.PLOS global public health · 2025Article
- Prevalence of aspiration pneumonia among stroke patients in Ethiopia: A systematic review and meta-analysis.PLOS global public health · 2025Article
- In-hospital mortality and its associated factors among hospitalized stroke patients at public hospitals of Eastern Ethiopia.BMC cardiovascular disorders · 2024Article
- Global Insights on Prehospital Stroke Care: A Comprehensive Review of Challenges and Solutions in Low- and Middle-Income Countries.Journal of clinical medicine · 2024Review
- 30-day in-hospital stroke case fatality and significant risk factors in sub-Saharan-Africa: A systematic review and meta-analysis.PLOS global public health · 2024Article
- The State of Stroke Research in Malawi: Results from a Mapping Review Study.Journal of multidisciplinary healthcare · 2024Review
- Knowledge of stroke risk factors and warning symptoms among adults with type 2 diabetes in Addis Ababa, Ethiopia, 2021: an institution-Based cross-sectional study.BMC cardiovascular disorders · 2023Article
- A Prospective Study of Stroke Characteristics, Risk Factors, and Mortality in a Tertiary Hospital of Northern Ethiopia.International journal of general medicine · 2023Article
- Factors associated with stroke associated pneumonia among adult stroke patients admitted to university of Gondar hospital, Northwest Ethiopia.Scientific reports · 2022Article
- Magnitude and Predictors of In-Hospital Stroke Mortality in Ethiopia: A Systematic Review and Meta-Analysis.Stroke research and treatment · 2022Review
- Comparison of Clotting and Inflammatory Biomarkers Between Young Hypertensive and Normotensive Adults in Ekiti State, Nigeria.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
objectiveTo assess the in-hospital mortality from acute stroke and its predictors in sub-Saharan Africa.
methodThe literature search was conducted in the databases of PubMed/Medline, Embase, CINAHL, and Google Scholar. The retrieved studies were screened by titles and abstracts, and then full texts were assessed for eligibility. The methodological quality of the included studies was assessed using the Joanna Briggs Institute's critical appraisal checklist. The publication bias was assessed using the funnel plot asymmetry and the Egger tests. Data were analyzed using Stata software version 15.0 in a random-effect model.
resultA total of 27 studies with a total sample size of 6331 were included in this systematic review and meta-analysis. The pooled estimated prevalence of in-hospital mortality due to stroke was 22% (95% confidence interval = 0.17-0.27). Stroke mortality in Western Africa (37%, 95% confidence interval = 0.24-0.50) was higher than in Eastern Africa (15%, 95% confidence interval = 0.12-0.19) and Southern Africa (18%, 95% confidence interval = 0.06-0.19). In three studies, mortality was higher in hemorrhagic stroke (25%) than ischemic stroke (14%). Risk factors associated with higher mortality were admission Glasgow Coma Scale, stroke severity, age, sex, presence of hypertension, and declined renal function.
conclusionThe in-patient mortality of stroke in sub-Saharan Africa was high. Therefore, there is an urgent need for further stroke epidemiology studies in stroke subtypes and the performance of patient-level meta-analysis to understand the risk factors associated with mortality and herald appropriate intervention to curb the high mortality rate in the region.
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