Evidence map›Paper›PMID 34377456›Full record

ArticleBritish journal of pain2021

Radiofrequency denervation of the lumbar facet joints: guidelines for the RADICAL randomised controlled trial.

Cathy Price, Barney Reeves, Alia Ahmad, Mohjir Baloch, Ganesan Baranidharan, Robin Correa, Tim McCormick, Manohar Sharma, Bala Veemarajan, Margot Grimwood and 2 more

Open access · hybridAbstract read
In one paragraph

Article in British journal of pain, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 1 country.

Cathy PriceSolent NHS Trust, Southampton, UK.ORCID https://orcid.org/0000-0003-0111-9364
Barney ReevesBristol Trials Centre, Bristol Medical School, University of Bristol, Bristol, UK.
Alia AhmadBarts Health NHS Trust, London, UK.
Mohjir BalochFrimley Health NHS Trust, Frimley, UK.
Ganesan BaranidharanLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Robin CorreaUniversity Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
Tim McCormickOxford University Hospitals NHS Trust, Oxford, UK.
Manohar SharmaThe Walton Centre NHS Foundation Trust, Liverpool, UK.
Bala VeemarajanSherwood Forest Hospital NHS Trust, Sutton-In-Ashfield, UK.
Margot GrimwoodSolent NHS Trust, Southampton, UK.
Katrina Ishbel PirieSolent NHS Trust, Southampton, UK.
Vikki WyldeBristol Trials Centre, Bristol Medical School, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0002-8460-1529
Solent NHS Trust · GBBarts Health NHS Trust · GBFrimley Park Hospital · GBLeeds Teaching Hospitals NHS Trust · GBOxford University Hospitals NHS Trust · GBSherwood Forest Hospitals NHS Foundation Trust · GBUniversity Hospitals Bristol NHS Foundation Trust · GBUniversity Hospitals Coventry and Warwickshire NHS Trust · GBUniversity of Bristol · GBUniversity of Liverpool · GB

Funding

Department of Health NIHR127457
6 · The paper itself

Abstract

BACKGROUND AND

aimThe RADICAL trial has been funded by the National Institute for Health Research (NIHR) to evaluate the clinical and cost-effectiveness of radiofrequency denervation (RFD) for low back pain. Recommendations have been published which aim to standardise selection of patients and RFD technique. However, it is important to ensure these recommendations are acceptable to clinicians within the context of the trial. The aim of this work was to develop standardised criteria for the trial entry and RFD technique for implementation within the RADICAL trial.

methodsFourteen pain clinicians completed a survey, which involved reviewing the current recommendations and indicating whether they disagreed with any of the recommendations and if so why. Responses were collated and presented at a half-day workshop with 14 attendees. During the workshop, the National Low Back and Radicular Pain Pathway (NLBRPP) guidelines for patient selection and an article by Eldabe and colleagues presenting recommendations on the RFD technique were reviewed. Attendees discussed whether each component of the recommendations should be mandatory, mandatory with alteration or clarification or optional within the RADICAL trial.

resultsAttendees agreed during the workshop that 5 of the 10 criteria for patient selection described in the NLBRPP should be mandatory within the RADICAL trial. Three were agreed as mandatory criteria but required further clarification, one of which involved defining a positive response to a diagnostic medial branch block as ⩾60% pain relief. Two criteria had optional components. After reviewing the recommendations on the RFD technique from Eldabe and colleagues, seven components were agreed as mandatory, three were mandatory with alterations and three were optional.

conclusionWhen evaluating complex interventions, such as RFD, it is important to ensure agreement and clarity on the clinical protocol, so that the intervention can be reproduced, if found to be effective.

Indexed as

chronic painLow back painpain clinicspain managementradiofrequency denervation

Identifiers

PMID34377456
PMCPMC8339950
OpenAlexW3042903725

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.