ArticleAnnals of medicine and surgery (2012)2021
Vitamin D deficiency and COVID-19: A case-control study at a tertiary care hospital in India.
Article in Annals of medicine and surgery (2012), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Is the vitamin D status of patients with COVID-19 associated with reduced mortality? A systematic review and meta-analysis.Archives of endocrinology and metabolism · 2023Pooled it
- Low 1,25-dihydroxyvitamin D levels are associated with severe COVID-19: an observational study in hospitalized patients.Frontiers in nutrition · 2026Article
- Effectiveness of Drug Repurposing and Natural Products Against SARS-CoV-2: A Comprehensive Review.Clinical pharmacology : advances and applications · 2024Review
- A systematic review: The relationship of COVID-19 to iron, zinc, and vitamin D.Journal of family medicine and primary care · 2023Article
- Effect of educational intervention on knowledge and attitude about the role of vitamins, minerals and nutraceuticals in COVID-19 and other disorders among medical and nursing undergraduates of a tertiary care teaching hospital.Clinical nutrition ESPEN · 2023Article
- Article
- The association between vitamin D intake with inflammatory and biochemical indices and mortality in critically ill patients with COVID-19: A case-control study.Immunity, inflammation and disease · 2023Article
- Association of Vitamin D Deficiency and Insufficiency with Pathology in Hospitalized Patients.Diagnostics (Basel, Switzerland) · 2023Article
- Are Low Serum Vitamin D Levels a Risk Factor for Advent of COVID-19 Associated Rhinocerebral Mucormycosis: A Preliminary Case Control Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022Article
- Vitamin D Levels and Length of Hospitalization in Indian Patients With COVID-19: A Single-Center Prospective Study.Cureus · 2022Article
- Vitamin D deficiency is associated with higher risks for SARS-CoV-2 infection and COVID-19 severity: a retrospective case-control study.Internal and emergency medicine · 2022Article
- An Epidemiological Investigation to evaluate the link between hypovitaminosis D and COVID-19.Journal of family medicine and primary care · 2022Article
- The Relationship Between Vitamin D Levels and Severity in Illness in COVID-19 Patients: A Cross-Sectional Study.Cureus · 2022Article
- Very Low Vitamin D Levels are a Strong Independent Predictor of Mortality in Hospitalized Patients with Severe COVID-19.Archives of medical research · 2022Article
- Upregulating Human Cathelicidin Antimicrobial Peptide LL-37 Expression May Prevent Severe COVID-19 Inflammatory Responses and Reduce Microthrombosis.Frontiers in immunology · 2022Review
- Association of Serum Vitamin D level and COVID-19 infection: A Case-control Study.Qatar medical journal · 2022Article
- Commentary on "Vitamin D deficiency and COVID-19: A case-control study at a tertiary care hospital in India".Annals of medicine and surgery (2012) · 2021Article
- The Renin-Angiotensin System: A Key Role in SARS-CoV-2-Induced COVID-19.Molecules (Basel, Switzerland) · 2021Review
- Coronavirus Disease (COVID-19) Control between Drug Repurposing and Vaccination: A Comprehensive Overview.Vaccines · 2021Review
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs the pandemic COVID-19 affected developing and developed countries, there is no proven treatment options available yet. The anti-inflammatory, antiviral and immune modulator effect of Vitamin D could be beneficial to COVID-19.
aimTo find out the possible association between Vitamin D and COVID-19.
methodsThe present case-control study was conducted at tertiary care hospital, AIIMS, Patna, Bihar, India. Total 156 cases and 204 controls were enrolled in the study after obtaining informed consent. Categorization of the patients were done based on clinical severity and level of Vitamin D. The association between these categories with different variables were analyzed using regression analysis and other statistical tests.
resultsThe status of Vitamin D (optimal, mild to moderate deficiency and severe deficiency) differed significantly among cases and controls. Diabetes and hypertension were most prevalent comorbidities among cases. On regression analysis, the difference in Vitamin D level was significant (aOR, 3.295; 95%CI, 1.25-8.685). The association between Vitamin D status and clinical severity group was statistically significant among cases. Among all variables, age, diabetes, hypertension and clinical severity were associated with worst outcome.
conclusionVitamin D status appears to be strongly associated with COVID-19 clinical severity. After COVID-19 confirmation, Vitamin D level should be measured in all patients and curative plus preventive therapy should be initiated.
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