Evidence map›Paper›PMID 34377422›Full record

ArticleChemical science2021

A unified strategy to prostaglandins: chemoenzymatic total synthesis of cloprostenol, bimatoprost, PGF

Kejie Zhu, Meifen Jiang, Baijun Ye, Guo-Tai Zhang, Weijian Li, Pei Tang, Zedu Huang, Fener Chen

Open access · greenAbstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. From Eye Care to Hair Growth: Bimatoprost.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kejie ZhuEngineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University 220 Handan Road Shanghai 200433 P. R. China huangzedu@fudan.edu.cn rfchen@fudan.edu.cn.
Meifen JiangEngineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University 220 Handan Road Shanghai 200433 P. R. China huangzedu@fudan.edu.cn rfchen@fudan.edu.cn.
Baijun YeEngineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University 220 Handan Road Shanghai 200433 P. R. China huangzedu@fudan.edu.cn rfchen@fudan.edu.cn.ORCID https://orcid.org/0000-0002-5485-2714
Guo-Tai ZhangSichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University Chengdu 610041 P. R. China.
Weijian LiSichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University Chengdu 610041 P. R. China.
Pei TangSichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University Chengdu 610041 P. R. China.
Zedu HuangEngineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University 220 Handan Road Shanghai 200433 P. R. China huangzedu@fudan.edu.cn rfchen@fudan.edu.cn.ORCID https://orcid.org/0000-0003-3320-3392
Fener ChenEngineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University 220 Handan Road Shanghai 200433 P. R. China huangzedu@fudan.edu.cn rfchen@fudan.edu.cn.ORCID https://orcid.org/0000-0002-6734-3388
Fudan University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Development of efficient and stereoselective synthesis of prostaglandins (PGs) is of utmost importance, owing to their valuable medicinal applications and unique chemical structures. We report here a unified synthesis of PGs cloprostenol, bimatoprost, PGF

Identifiers

PMID34377422
PMCPMC8336452
OpenAlexW3137938781

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.