Evidence map›Paper›PMID 34377399›Full record

ArticleChemical science2021

Harnessing α-l-fucosidase for

Seyoung Koo, Miae Won, Hao Li, Won Young Kim, Mingle Li, Chenxu Yan, Amit Sharma, Zhiqian Guo, Wei-Hong Zhu, Jonathan L Sessler and 2 more

Abstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Musculoskeletal imaging of senescence.Skeletal radiology · 2024
    Review
  8. Theranostic Fluorescent Probes.Chemical reviews · 2024
    Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Seyoung KooDepartment of Chemistry, Korea University Seoul 02841 Korea jongskim@korea.ac.kr.ORCID https://orcid.org/0000-0002-0620-5395
Miae WonDepartment of Chemistry, Korea University Seoul 02841 Korea jongskim@korea.ac.kr.ORCID https://orcid.org/0000-0002-1656-6362
Hao LiDepartment of Chemistry, Sungkyunkwan University Suwon 16419 Korea.
Won Young KimDepartment of Chemistry, Korea University Seoul 02841 Korea jongskim@korea.ac.kr.
Mingle LiDepartment of Chemistry, Korea University Seoul 02841 Korea jongskim@korea.ac.kr.ORCID https://orcid.org/0000-0002-0384-9128
Chenxu YanInstitute of Fine Chemicals, East China University of Science and Technology Shanghai 200237 China.ORCID https://orcid.org/0000-0001-7130-769X
Amit SharmaCSIR-Central Scientific Instruments Organisation Sector-30C Chandigarh 160030 India.ORCID https://orcid.org/0000-0003-2815-8208
Zhiqian GuoInstitute of Fine Chemicals, East China University of Science and Technology Shanghai 200237 China.ORCID https://orcid.org/0000-0002-2192-825X
Wei-Hong ZhuInstitute of Fine Chemicals, East China University of Science and Technology Shanghai 200237 China.ORCID https://orcid.org/0000-0001-9103-166X
Jonathan L SesslerDepartment of Chemistry, University of Texas at Austin Austin Texas 78712-1224 USA sessler@cm.utexas.edu.ORCID https://orcid.org/0000-0002-9576-1325
Jin Yong LeeDepartment of Chemistry, Sungkyunkwan University Suwon 16419 Korea.ORCID https://orcid.org/0000-0003-0360-5059
Jong Seung KimDepartment of Chemistry, Korea University Seoul 02841 Korea jongskim@korea.ac.kr.ORCID https://orcid.org/0000-0003-3477-1172

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precise detection of cellular senescence may allow its role in biological systems to be evaluated more effectively, while supporting studies of therapeutic candidates designed to evade its detrimental effect on physical function. We report here studies of α-l-fucosidase (α-fuc) as a biomarker for cellular senescence and the development of an α-fuc-responsive aggregation induced emission (AIE) probe, termed

Identifiers

PMID34377399
PMCPMC8317655

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.