Evidence map›Paper›PMID 34377299›Full record

ArticleAmerican journal of translational research2021

Serum cortisol levels and adrenal gland size in patients with chronic obstructive pulmonary disease.

Peng Wei, Yu Li, Lijuan Wu, Junhong Wu, Wenbin Wu, Shuping Chen, Shujuan Qin, Jiemei Feng

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Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Peng WeiDepartment of Pulmonary and Critical Care Medicine, Guigang City People's Hospital Guigang, Guangxi Zhuang Autonomous Region, China.
Yu LiDepartment of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Guangxi Medical University Nanning, Guangxi Zhuang Autonomous Region, China.
Lijuan WuDepartment of Ultrasound, Guigang City People's Hospital Guigang, Guangxi Zhuang Autonomous Region, China.
Junhong WuDepartment of Radiology, Guigang City People's Hospital Guigang, Guangxi Zhuang Autonomous Region, China.
Wenbin WuDepartment of Pulmonary and Critical Care Medicine, Guigang City People's Hospital Guigang, Guangxi Zhuang Autonomous Region, China.
Shuping ChenDepartment of Pulmonary and Critical Care Medicine, Guigang City People's Hospital Guigang, Guangxi Zhuang Autonomous Region, China.
Shujuan QinDepartment of Pulmonary and Critical Care Medicine, Guigang City People's Hospital Guigang, Guangxi Zhuang Autonomous Region, China.
Jiemei FengDepartment of Pulmonary and Critical Care Medicine, Guigang City People's Hospital Guigang, Guangxi Zhuang Autonomous Region, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the clinical significance of serum Cortisol (Cor) levels and adrenal gland size in patients with chronic obstructive pulmonary disease (COPD).

methodsWe assigned 80 patients with COPD admitted to our hospital to an observation group, and 80 healthy individuals to a control group. Serum Cor, C-reactive protein (CRP) level, and adrenal gland size were measured. Patients with COPD were divided into several subgroups according to BODE (BMI, Obstruction, Dyspnea, Exercise capacity) indexes and forced expiratory volume in the first second (FEV1), and Cor levels and adrenal gland size were compared between subgroups. The Pearson Correlation was used to analyze correlations of adrenal gland size and Cor levels with partial pressure of oxygen (PaO

resultsIncreased serum CRP levels were found in the observation group, while Cor levels and adrenal gland diameter were decreased (P<0.05 for each comparison). In the observation group, an increase in BODE index or decrease in FEV1 led to decreased Cor levels and adrenal gland diameter, as well as increased CRP levels (P<0.05, each comparison). Correlation analysis showed that adrenal gland diameter and Cor levels were positively correlated with PaO

conclusionCor levels and adrenal gland size are closely associated with the severity of COPD, and Cor levels are predictive of prognosis.

Indexed as

adrenal glandChronic obstructive pulmonary diseasecortisolprognosis

Identifiers

PMID34377299
PMCPMC8340202

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.