ArticleAmerican journal of translational research2021
The correlation of serum Vaspin, S100A12 and PCT levels with the severity of ulcerative colitis and its clinical significance.
Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.
- A genome- and phenome-wide association study of plasma procalcitonin concentrations in individuals of European ancestry.EBioMedicine · 2026Pooled it
- Analysis of serum S100A12, soluble advanced glycation end products receptor, and gut microbiome in elderly patients with colorectal cancer.World journal of gastrointestinal oncology · 2025Article
- Specific labeling of outer membrane vesicles with antibiotic-conjugated probe reveals early bacterial infections in blood.Nature communications · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to investigate the correlation between Vaspin, S100A12 and PCT levels and ulcerative colitis (UC).
methodsThis study included 104 patients with UC from November 2018 to June 2020 as the experimental group, including 37 cases in remission and 67 cases in an active phase; patients in an active phase were classified into 17 cases of mild, 37 cases of moderate and 13 cases of severe according to Modified Mayo Endoscopic Score (MMES). There were 104 patients as healthy controls during the same period who were enrolled as the control group. Serum levels of Vaspin, S100A12, PCT, inflammatory factors and immunoglobulins were compared between two groups and the correlation between serum levels of each index and the severity of UC was analyzed.
resultsCompared with the control group, serum Vaspin, S100A12, and PCT levels were higher in the experimental group, and serum Vaspin, S100A12, and PCT levels were higher in the active phase than in the remission phase (P < 0.05). Serum Vaspin, S100A12, PCT, IL-6, IL-17, TNF-α levels: Severe patients > moderate patients > mild patients; Serum IgA, IgG levels: Severe < moderate < mild (P < 0.05). As shown by Spearman analysis, serum Vaspin, S100A12, PCT, IL-6, IL-17, and TNF-α levels were positively correlated with (r=0.317,
conclusionSerum Vaspin, S100A12, PCT and inflammatory factor levels were positively correlated with the severity of UC disease, and they showed significance in the assessment of the severity and prognosis of UC.
Indexed as
Identifiers
34377270PMC8340175W3192077473What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.