ArticleIntegrative medicine (Encinitas, Calif.)2021
Homemade Elemental Diet to Treat Intestinal Methanogen Overgrowth: A Case Report.
Article in Integrative medicine (Encinitas, Calif.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 3 citations in OpenAlex.
- IBS and SIBO: Gut Microbiota, Pathophysiology, and Non-Pharmacological Interventions.Antibiotics (Basel, Switzerland) · 2026Review
- Small intestinal bacterial overgrowth and intestinal methanogen overgrowth in gastrointestinal malignancies.Contemporary oncology (Poznan, Poland) · 2025Review
- Archaea in the Human Microbiome and Potential Effects on Human Infectious Disease.Emerging infectious diseases · 2024Review
- Association between Gut Dysbiosis and the Occurrence of SIBO, LIBO, SIFO and IMO.Microorganisms · 2023Review
- Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth: Are They Overdiagnosed?Acta gastroenterologica LatinoamericanaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThis case report documented the outcome of consuming a 14-day homemade elemental diet to normalize intestinal methanogen overgrowth. A prevention protocol after methanogen eradication was employed to prevent recurrence. PRESENTING CONCERNS: The patient was a 47-year-old White female with intestinal methanogen overgrowth confirmed by lactulose breath testing. THERAPEUTIC FOCUS AND ASSESSMENT: Therapeutic interventions consisted of the homemade elemental diet, carbohydrate modified diet, lifestyle modifications, pharmaceutical and herbal prokinetics, and a probiotic supplement. FOLLOW-UP AND OUTCOMES: The homemade elemental diet was conducted for 14 days. The lactulose breath test results on day 15 indicated a reduction of methane levels from an average of 42 ppm to 3 ppm throughout the testing period (120 minutes). The standard prevention protocol of prokinetics, diet, and lifestyle were not effective at preventing relapse. A repeat lactulose breath test on day 122 was positive, with an average of 81 ppm methane. The elemental diet was repeated for 9 days, with fasting on day 10. The lactulose breath test on day 11 indicated a reduction of methane gas to an average of 23 ppm.
conclusionThe homemade elemental diet resulted in a substantial reduction in methane and symptom resolution. It is another treatment option for patients with intestinal methanogen overgrowth.
Identifiers
34377092PMC8325492W3189409226What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.