Evidence map›Paper›PMID 34377049›Full record

ArticleTurkish journal of biology = Turk biyoloji dergisi2021

Crosstalk between autophagy and DNA repair systems.

Sinem Demirbağ-Sarikaya, Hatice Çakir, Devrim Gözüaçik, Yunus Akkoç

Abstract read
In one paragraph

Article in Turkish journal of biology = Turk biyoloji dergisi, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Telomeric autophagy in human health, aging, and diseases.Frontiers in molecular biosciences · 2026
    Review
  5. Review
  6. Autophagy: The convergence point of aging and cancer.Biochemistry and biophysics reports · 2025
    Review
  7. Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sinem Demirbağ-SarikayaSUNUM Nanotechnology Research and Application Center, İstanbul Turkey.ORCID https://orcid.org/0000-0002-8626-1556
Hatice ÇakirSUNUM Nanotechnology Research and Application Center, İstanbul Turkey.ORCID https://orcid.org/0000-0003-0523-7210
Devrim GözüaçikSUNUM Nanotechnology Research and Application Center, İstanbul Turkey.ORCID https://orcid.org/0000-0001-7739-2346
Yunus AkkoçKoç University Research Center for Translational Medicine (KUTTAM), İstanbul Turkey.ORCID https://orcid.org/0000-0001-5379-6151

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy and DNA repair are two essential biological mechanisms that maintain cellular homeostasis. Impairment of these mechanisms was associated with several pathologies such as premature aging, neurodegenerative diseases, and cancer. Intrinsic or extrinsic stress stimuli (e.g., reactive oxygen species or ionizing radiation) cause DNA damage. As a biological stress response, autophagy is activated following insults that threaten DNA integrity. Hence, in collaboration with DNA damage repair and response mechanisms, autophagy contributes to the maintenance of genomic stability and integrity. Yet, connections and interactions between these two systems are not fully understood. In this review article, current status of the associations and crosstalk between autophagy and DNA repair systems is documented and discussed.

Indexed as

AutophagyDDRDNA damageDNA repair

Identifiers

PMID34377049
PMCPMC8313936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.