Evidence map›Paper›PMID 34376994›Full record

ReviewInfectious diseases2021

COVID-19 and Antimicrobial Resistance: A Review.

Yusuff Adebayo Adebisi, Aishat Jumoke Alaran, Melody Okereke, Gabriel Ilerioluwa Oke, Oladunni Abimbola Amos, Omotayo Carolyn Olaoye, Iyiola Oladunjoye, Azeez Yusuff Olanrewaju, Nelson Ashinedu Ukor, Don Eliseo Lucero-Prisno

Open access · goldAbstract readReview
In one paragraph

Review in Infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
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  19. Semisynthetic Amides of Amphotericin B and Nystatin AAntibiotics (Basel, Switzerland) · 2023
    Article
  20. Case report: Successful treatment of recurrentFrontiers in pharmacology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 2 countries.

Yusuff Adebayo AdebisiFaculty of Pharmacy, University of Ibadan, Ibadan, Nigeria.ORCID https://orcid.org/0000-0002-2381-0984
Aishat Jumoke AlaranNational Institute for Pharmaceutical Research and Development, Abuja, Nigeria.
Melody OkerekeFaculty of Pharmaceutical Sciences, University of Ilorin, Ilorin, Kwara State, Nigeria.
Gabriel Ilerioluwa OkeDepartment of Medical Laboratory Science, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.ORCID https://orcid.org/0000-0002-0890-8895
Oladunni Abimbola AmosFaculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria, Nigeria.
Omotayo Carolyn OlaoyeFaculty of Pharmacy, Obafemi Awolowo University Ile-Ife, Jos, Nigeria.ORCID https://orcid.org/0000-0001-9886-6109
Iyiola OladunjoyeDepartment of Microbiology, University of Ilorin, Ilorin, Kwara State, Nigeria.ORCID https://orcid.org/0000-0002-6760-5448
Azeez Yusuff OlanrewajuFaculty of Pharmacy, University of Ibadan, Ibadan, Nigeria.
Nelson Ashinedu UkorFaculty of Pharmaceutical Sciences, University of Uyo, Uyo, Nigeria.
Don Eliseo Lucero-PrisnoDepartment of Global Health and Development, London School of Hygiene and Tropical Medicine, London, UK.
University of Ibadan · NGUniversity of Ilorin · NGAhmadu Bello University · NGLadoke Akintola University of Technology · NGLondon School of Hygiene & Tropical Medicine · GBNational Institute for Pharmaceutical Research and Development · NGObafemi Awolowo University · NGUniversity of Uyo · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the world continues to respond to the coronavirus pandemic (COVID-19), there is a larger hidden threat of antimicrobial resistance (AMR) lurking behind. AMR remains worrisome in that the pathogens causing resistant infections to thrive in hospitals and medical facilities, putting all patients at risk, irrespective of the severity of their medical conditions, further compounding the management of COVID-19. This study aims to provide overview of early findings on COVID-19 and AMR as well as to provide recommendations and lesson learned toward improving antimicrobial stewardship. We conducted a rapid narrative review of published articles by searching PubMed and Google Scholar on COVID-19 and Antimicrobial Resistance with predetermined keywords. Secondary bacterial infections play crucial roles in mortality and morbidity associated with COVID-19. Research has shown that a minority of COVID-19 patients need antibiotics to treat secondary bacterial infections. Current evidence reiterates the need not to give antibiotic therapy or prophylaxis to patients with mild COVID-19 or to patients with suspected or confirmed moderate COVID-19 illness unless it is indicated. The pandemic has also brought to the fore the deficiencies in health systems around the world. This comes with a lot of lessons, one of which is that despite the advances in medicine; we remain incredibly vulnerable to infections with limited or no standard therapies. This is worth thinking in the context of AMR, as the resistant pathogens are evolving and leading us to the era of untreatable infections. There is a necessity for continuous research into understanding and controlling infectious agents, as well as the development of newer functional antimicrobials and the need to strengthen the antimicrobial stewardship programs.

Indexed as

2019-nCoVantimicrobial resistanceantimicrobial stewardshipCOVID-19pandemicSARS-CoV-2

Identifiers

PMID34376994
PMCPMC8327234
OpenAlexW3191174661

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.